Structural mechanisms for centrosomal recruitment and organization of the microtubule nucleator γ-TuRC

Structural mechanisms for centrosomal recruitment and organization of the microtubule nucleator γ-TuRC

Abstract The γ-tubulin ring complex (γ-TuRC) acts as a structural template for microtubule formation at centrosomes, associating with two main compartments: the pericentriolar material and the centriole lumen. In the pericentriolar material, the γ-TuRC is involved in microtubule organization, while...

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Main Authors: Qi Gao, Florian W. Hofer, Sebastian Filbeck, Bram J. A. Vermeulen, Martin Würtz, Annett Neuner, Charlotte Kaplan, Maja Zezlina, Cornelia Sala, Hyesu Shin, Oliver J. Gruss, Elmar Schiebel, Stefan Pfeffer
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57729-2
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