Assessment of the variability and correlation of biometric measurements in eyes with cataracts
Purpose: To assess the variability and correlation of ocular biometric parameters in eyes with cataracts and examine their association with age and gender. Methods: A retrospective analysis was performed on biometric data from 7,458 eyes without retinal pathologies, using an optical biometer equippe...
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Elsevier
2025-02-01
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| Series: | Photodiagnosis and Photodynamic Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1572100024004897 |
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| author | Jian-Feng Zhao Chen Yang Jie Zhou Hai-Yan Zhang Yu Geng |
| author_facet | Jian-Feng Zhao Chen Yang Jie Zhou Hai-Yan Zhang Yu Geng |
| author_sort | Jian-Feng Zhao |
| collection | DOAJ |
| description | Purpose: To assess the variability and correlation of ocular biometric parameters in eyes with cataracts and examine their association with age and gender. Methods: A retrospective analysis was performed on biometric data from 7,458 eyes without retinal pathologies, using an optical biometer equipped with low-coherence reflectometry technology. Pearson's correlation coefficients (r) were used to evaluate the relationships between age, gender, and various ocular parameters, including axial length (AL), anterior chamber depth (ACD), lens thickness (LT), central corneal thickness (CCT), corneal refractive power (Km), and white-to-white (WTW) measurement. Results: The mean AL was 23.82 ± 1.83 mm (SD). Among the study cohort, 8.0 % (593 eyes) were categorized as having short AL (AL ≤ 22 mm), 60.5 % (4,520 eyes) as having normal AL (22 mm < AL ≤ 24 mm), 21.2 % (1,579 eyes) as having long AL (24 mm < AL ≤ 26 mm), and 10.3 % (766 eyes) as having a AL (> 26 mm). The mean age of the cohort was 64.18 ± 14.95 years (range: 18 - 98 years), with males averaging 56.53 ± 13.88 years and females averaging 72.19 ± 11.41 years. Mean values for ACD, LT, Km, CCT, WTW, and angle kappa were found to vary with both age and gender. Males demonstrated significantly longer AL, deeper ACD, thicker LT, larger WTW, and lower Km compared to females (P < 0.05). Although males exhibited a greater anterior segment length (ASL), this difference did not reach statistical significance (P > 0.05). No significant correlation was found between ACD and AL in the short and long AL groups, while a positive correlation was observed in the normal and long AL groups. Additionally, LT demonstrated a negative correlation with AL in the normal AL group but a positive correlation in the long AL group. Conclusions: Cataracts develop at a greater age in female patients than in males. Ocular biometric parameters, including ACD, LT, CCT, Km, and (WTW) measurement, are influenced by age and gender. Lens thickness is the primary factor affecting ACD, though CCT, Km, and WTW also play significant roles. Furthermore, a negative correlation between AL and LT was identified, with variations depending on AL classification. |
| format | Article |
| id | doaj-art-74ce4e74764d426baf133a4f0395c996 |
| institution | Kabale University |
| issn | 1572-1000 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Photodiagnosis and Photodynamic Therapy |
| spelling | doaj-art-74ce4e74764d426baf133a4f0395c9962025-02-01T04:11:45ZengElsevierPhotodiagnosis and Photodynamic Therapy1572-10002025-02-0151104453Assessment of the variability and correlation of biometric measurements in eyes with cataractsJian-Feng Zhao0Chen Yang1Jie Zhou2Hai-Yan Zhang3Yu Geng4Department of Ophthalmology, The First Affiliated Hospital of Kunming Medical University, Kunming 650031, ChinaDepartment of Ophthalmology, The First Affiliated Hospital of Kunming Medical University, Kunming 650031, ChinaDepartment of Ophthalmology, The First Affiliated Hospital of Kunming Medical University, Kunming 650031, ChinaDepartment of Ophthalmology, The First Affiliated Hospital of Kunming Medical University, Kunming 650031, ChinaCorresponding author at: Department of Ophthalmology, The First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, 650031, China.; Department of Ophthalmology, The First Affiliated Hospital of Kunming Medical University, Kunming 650031, ChinaPurpose: To assess the variability and correlation of ocular biometric parameters in eyes with cataracts and examine their association with age and gender. Methods: A retrospective analysis was performed on biometric data from 7,458 eyes without retinal pathologies, using an optical biometer equipped with low-coherence reflectometry technology. Pearson's correlation coefficients (r) were used to evaluate the relationships between age, gender, and various ocular parameters, including axial length (AL), anterior chamber depth (ACD), lens thickness (LT), central corneal thickness (CCT), corneal refractive power (Km), and white-to-white (WTW) measurement. Results: The mean AL was 23.82 ± 1.83 mm (SD). Among the study cohort, 8.0 % (593 eyes) were categorized as having short AL (AL ≤ 22 mm), 60.5 % (4,520 eyes) as having normal AL (22 mm < AL ≤ 24 mm), 21.2 % (1,579 eyes) as having long AL (24 mm < AL ≤ 26 mm), and 10.3 % (766 eyes) as having a AL (> 26 mm). The mean age of the cohort was 64.18 ± 14.95 years (range: 18 - 98 years), with males averaging 56.53 ± 13.88 years and females averaging 72.19 ± 11.41 years. Mean values for ACD, LT, Km, CCT, WTW, and angle kappa were found to vary with both age and gender. Males demonstrated significantly longer AL, deeper ACD, thicker LT, larger WTW, and lower Km compared to females (P < 0.05). Although males exhibited a greater anterior segment length (ASL), this difference did not reach statistical significance (P > 0.05). No significant correlation was found between ACD and AL in the short and long AL groups, while a positive correlation was observed in the normal and long AL groups. Additionally, LT demonstrated a negative correlation with AL in the normal AL group but a positive correlation in the long AL group. Conclusions: Cataracts develop at a greater age in female patients than in males. Ocular biometric parameters, including ACD, LT, CCT, Km, and (WTW) measurement, are influenced by age and gender. Lens thickness is the primary factor affecting ACD, though CCT, Km, and WTW also play significant roles. Furthermore, a negative correlation between AL and LT was identified, with variations depending on AL classification.http://www.sciencedirect.com/science/article/pii/S1572100024004897Anterior chamber depthAxial lengthCataract surgeryLens thicknessLenstar LS900OCT |
| spellingShingle | Jian-Feng Zhao Chen Yang Jie Zhou Hai-Yan Zhang Yu Geng Assessment of the variability and correlation of biometric measurements in eyes with cataracts Photodiagnosis and Photodynamic Therapy Anterior chamber depth Axial length Cataract surgery Lens thickness Lenstar LS900 OCT |
| title | Assessment of the variability and correlation of biometric measurements in eyes with cataracts |
| title_full | Assessment of the variability and correlation of biometric measurements in eyes with cataracts |
| title_fullStr | Assessment of the variability and correlation of biometric measurements in eyes with cataracts |
| title_full_unstemmed | Assessment of the variability and correlation of biometric measurements in eyes with cataracts |
| title_short | Assessment of the variability and correlation of biometric measurements in eyes with cataracts |
| title_sort | assessment of the variability and correlation of biometric measurements in eyes with cataracts |
| topic | Anterior chamber depth Axial length Cataract surgery Lens thickness Lenstar LS900 OCT |
| url | http://www.sciencedirect.com/science/article/pii/S1572100024004897 |
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