Quasispecies Changes with Distinctive Point Mutations in the Hepatitis C Virus Internal Ribosome Entry Site (IRES) Derived from PBMCs and Plasma

Quasispecies Changes with Distinctive Point Mutations in the Hepatitis C Virus Internal Ribosome Entry Site (IRES) Derived from PBMCs and Plasma

The 5’ untranslated region (UTR) of the hepatitis C virus (HCV) genome contains the internal ribosome entry site (IRES), a highly conserved RNA structure essential for cap-independent translation of the viral polyprotein. HCV, apart from the liver, is thought to be associated with lymphocyte subpopu...

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Bibliographic Details
Main Authors: Luca Mercuri, Emma C. Thomson, Joseph Hughes, Peter Karayiannis
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Advances in Virology
Online Access:http://dx.doi.org/10.1155/2018/4835252
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