Expanding the CAR toolbox with high throughput screening strategies for CAR domain exploration: a comprehensive review

Chimeric antigen receptor (CAR)-T-cell therapy has been highly successful in the treatment of B-cell hematological malignancies. CARs are modular synthetic molecules that can redirect immune cells towards target cells with antibody-like specificity. Despite their modularity, CARs used in the clinic...

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Bibliographic Details
Main Authors: Sebastien Anguille, Eva Lion, Khloe S Gordon, Michael E Birnbaum, Gils Roex
Format: Article
Language:English
Published: BMJ Publishing Group 2025-04-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/4/e010658.full
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