A Young Woman with Common Variable Immunodeficiency: The Role of Thorough Medical History and Physical Examination in Accurate Diagnosis

Common variable immunodeficiency (CVID) is a rare immunodeficiency syndrome which presents with wide manifestations leading to delayed diagnosis. A 34-year-old woman presented to our hospital complaining of dyspnea and productive cough. Lung CT scan revealed loculated right-sided pleural effusion wi...

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Main Authors: Amirhossein Khodadadi, Rozita Khodashahi
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2024/4028888
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author Amirhossein Khodadadi
Rozita Khodashahi
author_facet Amirhossein Khodadadi
Rozita Khodashahi
author_sort Amirhossein Khodadadi
collection DOAJ
description Common variable immunodeficiency (CVID) is a rare immunodeficiency syndrome which presents with wide manifestations leading to delayed diagnosis. A 34-year-old woman presented to our hospital complaining of dyspnea and productive cough. Lung CT scan revealed loculated right-sided pleural effusion with bronchiectasis and consolidation in right lower lobes. After taking medical history and physical examination, we suspected CVID and ordered serum immunoglobulin levels. The laboratory results were in line with CVID diagnosis and showed decreased levels of IgG, IgM, and IgA. The patient was started on intravenous immune globulin (IVIG) therapy every month. After 3-month follow-up, the patient reported no problem and felt better.
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spelling doaj-art-74bfeb6d9c664ebda1467166f46d99492025-08-20T03:19:16ZengWileyCase Reports in Medicine1687-96352024-01-01202410.1155/2024/4028888A Young Woman with Common Variable Immunodeficiency: The Role of Thorough Medical History and Physical Examination in Accurate DiagnosisAmirhossein Khodadadi0Rozita Khodashahi1School of MedicineTransplant Research CenterCommon variable immunodeficiency (CVID) is a rare immunodeficiency syndrome which presents with wide manifestations leading to delayed diagnosis. A 34-year-old woman presented to our hospital complaining of dyspnea and productive cough. Lung CT scan revealed loculated right-sided pleural effusion with bronchiectasis and consolidation in right lower lobes. After taking medical history and physical examination, we suspected CVID and ordered serum immunoglobulin levels. The laboratory results were in line with CVID diagnosis and showed decreased levels of IgG, IgM, and IgA. The patient was started on intravenous immune globulin (IVIG) therapy every month. After 3-month follow-up, the patient reported no problem and felt better.http://dx.doi.org/10.1155/2024/4028888
spellingShingle Amirhossein Khodadadi
Rozita Khodashahi
A Young Woman with Common Variable Immunodeficiency: The Role of Thorough Medical History and Physical Examination in Accurate Diagnosis
Case Reports in Medicine
title A Young Woman with Common Variable Immunodeficiency: The Role of Thorough Medical History and Physical Examination in Accurate Diagnosis
title_full A Young Woman with Common Variable Immunodeficiency: The Role of Thorough Medical History and Physical Examination in Accurate Diagnosis
title_fullStr A Young Woman with Common Variable Immunodeficiency: The Role of Thorough Medical History and Physical Examination in Accurate Diagnosis
title_full_unstemmed A Young Woman with Common Variable Immunodeficiency: The Role of Thorough Medical History and Physical Examination in Accurate Diagnosis
title_short A Young Woman with Common Variable Immunodeficiency: The Role of Thorough Medical History and Physical Examination in Accurate Diagnosis
title_sort young woman with common variable immunodeficiency the role of thorough medical history and physical examination in accurate diagnosis
url http://dx.doi.org/10.1155/2024/4028888
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