Translational bioethics in nursing: a conceptual review of definitions, applications and ethical implications

Abstract Background Bioethics is fundamental in healthcare, guiding ethical decision-making and patient care. Translational bioethics (TB) aims to bridge the gap between ethical theories and real-world practice, including nursing. However, the concept of TB has not been clearly examined yet. Therefo...

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Main Authors: Frederick Acheampong Nimo, Abigail Gyamfi-Samakome, Esther Naana Gyan, Richard Argoh, Godson Obeng Ofori, Patience Fakornam Doe, Christian Makafui Boso
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medical Ethics
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Online Access:https://doi.org/10.1186/s12910-025-01264-8
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author Frederick Acheampong Nimo
Abigail Gyamfi-Samakome
Esther Naana Gyan
Richard Argoh
Godson Obeng Ofori
Patience Fakornam Doe
Christian Makafui Boso
author_facet Frederick Acheampong Nimo
Abigail Gyamfi-Samakome
Esther Naana Gyan
Richard Argoh
Godson Obeng Ofori
Patience Fakornam Doe
Christian Makafui Boso
author_sort Frederick Acheampong Nimo
collection DOAJ
description Abstract Background Bioethics is fundamental in healthcare, guiding ethical decision-making and patient care. Translational bioethics (TB) aims to bridge the gap between ethical theories and real-world practice, including nursing. However, the concept of TB has not been clearly examined yet. Therefore, this concept analysis was done to provide clarity and practical meaning to the concept of translational bioethics within the context of nursing. Methods Walker and Avant’s concept analysis framework was employed to examine TB and apply it to nursing practice. A systematic search of electronic databases, including PubMed, Google Scholar, and PubMed Central, was conducted. Papers were screened and twenty-five eligible full-text records included in analysis. Results The analysis identified four key defining attributes of TB, including bridging the theory-practice gap, ethical evaluation and decision making, interdisciplinary collaboration, social responsibility and societal impact. Antecedents included ethical dilemmas, identifying theory-practice gaps, and commitment to real-world impact. The consequences of TB encompassed improved patient care, reduction of ethical conflicts, positive social impact, and informed policy and decision making. Conclusions This study provided a clear conceptual model of TB, offering insights into its antecedents, attributes, and consequences. Translational bioethics can be defined as an approach that bridges ethical theory and practice through research, interdisciplinary collaboration, and a focus on contextual ethical evaluation and decision making, aiming for socially responsible and impactful outcomes.
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spelling doaj-art-74b1b8cd8d2f4009b7bd10ac2e9e77ea2025-08-20T03:41:56ZengBMCBMC Medical Ethics1472-69392025-07-012611910.1186/s12910-025-01264-8Translational bioethics in nursing: a conceptual review of definitions, applications and ethical implicationsFrederick Acheampong Nimo0Abigail Gyamfi-Samakome1Esther Naana Gyan2Richard Argoh3Godson Obeng Ofori4Patience Fakornam Doe5Christian Makafui Boso6Department of Adult Health, School of Nursing and Midwifery, University of Cape CoastDepartment of Adult Health, School of Nursing and Midwifery, University of Cape CoastDepartment of Adult Health, School of Nursing and Midwifery, University of Cape CoastDepartment of Public Health, School of Nursing and Midwifery, University of Cape CoastDepartment of Adult Health, School of Nursing and Midwifery, University of Cape CoastDepartment of Public Health, School of Nursing and Midwifery, University of Cape CoastDepartment of Adult Health, School of Nursing and Midwifery, University of Cape CoastAbstract Background Bioethics is fundamental in healthcare, guiding ethical decision-making and patient care. Translational bioethics (TB) aims to bridge the gap between ethical theories and real-world practice, including nursing. However, the concept of TB has not been clearly examined yet. Therefore, this concept analysis was done to provide clarity and practical meaning to the concept of translational bioethics within the context of nursing. Methods Walker and Avant’s concept analysis framework was employed to examine TB and apply it to nursing practice. A systematic search of electronic databases, including PubMed, Google Scholar, and PubMed Central, was conducted. Papers were screened and twenty-five eligible full-text records included in analysis. Results The analysis identified four key defining attributes of TB, including bridging the theory-practice gap, ethical evaluation and decision making, interdisciplinary collaboration, social responsibility and societal impact. Antecedents included ethical dilemmas, identifying theory-practice gaps, and commitment to real-world impact. The consequences of TB encompassed improved patient care, reduction of ethical conflicts, positive social impact, and informed policy and decision making. Conclusions This study provided a clear conceptual model of TB, offering insights into its antecedents, attributes, and consequences. Translational bioethics can be defined as an approach that bridges ethical theory and practice through research, interdisciplinary collaboration, and a focus on contextual ethical evaluation and decision making, aiming for socially responsible and impactful outcomes.https://doi.org/10.1186/s12910-025-01264-8Concept analysisEthical decision-makingInterdisciplinary collaborationNursing ethicsTheory-practice gapTranslational bioethics
spellingShingle Frederick Acheampong Nimo
Abigail Gyamfi-Samakome
Esther Naana Gyan
Richard Argoh
Godson Obeng Ofori
Patience Fakornam Doe
Christian Makafui Boso
Translational bioethics in nursing: a conceptual review of definitions, applications and ethical implications
BMC Medical Ethics
Concept analysis
Ethical decision-making
Interdisciplinary collaboration
Nursing ethics
Theory-practice gap
Translational bioethics
title Translational bioethics in nursing: a conceptual review of definitions, applications and ethical implications
title_full Translational bioethics in nursing: a conceptual review of definitions, applications and ethical implications
title_fullStr Translational bioethics in nursing: a conceptual review of definitions, applications and ethical implications
title_full_unstemmed Translational bioethics in nursing: a conceptual review of definitions, applications and ethical implications
title_short Translational bioethics in nursing: a conceptual review of definitions, applications and ethical implications
title_sort translational bioethics in nursing a conceptual review of definitions applications and ethical implications
topic Concept analysis
Ethical decision-making
Interdisciplinary collaboration
Nursing ethics
Theory-practice gap
Translational bioethics
url https://doi.org/10.1186/s12910-025-01264-8
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