Can cell-cultured meat from stem cells pave the way for sustainable alternative protein?

As the global population grows, the demand for food and animal-derived products rises significantly, posing a notable challenge to the progress of society in general. Alternative protein production may adequately address such a challenge, and cell-based meat production emerges as a promising solutio...

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Main Authors: Octavio Bignardi da Silva Nunes, Tiago Willian Buranello, Fabiana de Andrade Farias, Jenyffer Rosero, Kaiana Recchia, Fabiana Fernandes Bressan
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Food Science
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Online Access:http://www.sciencedirect.com/science/article/pii/S2665927125000103
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author Octavio Bignardi da Silva Nunes
Tiago Willian Buranello
Fabiana de Andrade Farias
Jenyffer Rosero
Kaiana Recchia
Fabiana Fernandes Bressan
author_facet Octavio Bignardi da Silva Nunes
Tiago Willian Buranello
Fabiana de Andrade Farias
Jenyffer Rosero
Kaiana Recchia
Fabiana Fernandes Bressan
author_sort Octavio Bignardi da Silva Nunes
collection DOAJ
description As the global population grows, the demand for food and animal-derived products rises significantly, posing a notable challenge to the progress of society in general. Alternative protein production may adequately address such a challenge, and cell-based meat production emerges as a promising solution. This review investigates methodologies for in vitro myogenesis and adipogenesis from stem cells (adult, embryonic, or induced pluripotent stem cells - iPSCs) across different animal species, as well as the remaining challenges for scalability, the possibility of genetic modification, along with safety concerns regarding the commercialization of cell-cultured meat. Regarding such complexities, interdisciplinary approaches will be vital for assessing the potential of cell-cultured meat as a sustainable protein source, mimicking the sensory and nutritional attributes of conventional livestock meat whilst meeting the demands of a growing global population while mitigating environmental impacts.
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series Current Research in Food Science
spelling doaj-art-74aceb919b70416daff263df4501a2cf2025-08-20T02:06:30ZengElsevierCurrent Research in Food Science2665-92712025-01-011010097910.1016/j.crfs.2025.100979Can cell-cultured meat from stem cells pave the way for sustainable alternative protein?Octavio Bignardi da Silva Nunes0Tiago Willian Buranello1Fabiana de Andrade Farias2Jenyffer Rosero3Kaiana Recchia4Fabiana Fernandes Bressan5Department of Food Engineering, Faculty of Animal Sciences and Food Engineering, University of São Paulo 13635-000, Pirassununga, SP, Brazil; Department of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering, University of São Paulo 13635-000, Pirassununga, SP, BrazilDepartment of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering, University of São Paulo 13635-000, Pirassununga, SP, Brazil; Postgraduate Program in Anatomy of Domestic and Wils Species, Faculty of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo 01001-010, SP, BrazilDepartment of Food Engineering, Faculty of Animal Sciences and Food Engineering, University of São Paulo 13635-000, Pirassununga, SP, Brazil; Department of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering, University of São Paulo 13635-000, Pirassununga, SP, BrazilDepartment of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering, University of São Paulo 13635-000, Pirassununga, SP, Brazil; Postgraduate Program in Anatomy of Domestic and Wils Species, Faculty of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo 01001-010, SP, BrazilDepartment of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering, University of São Paulo 13635-000, Pirassununga, SP, Brazil; Postgraduate Program in Anatomy of Domestic and Wils Species, Faculty of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo 01001-010, SP, BrazilDepartment of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering, University of São Paulo 13635-000, Pirassununga, SP, Brazil; Postgraduate Program in Anatomy of Domestic and Wils Species, Faculty of Veterinary Medicine and Animal Sciences, University of São Paulo, São Paulo 01001-010, SP, Brazil; Corresponding author. Department of Veterinary Medicine, Faculty of Animal Sciences and Food Engineering, University of São Paulo 13635-000, Pirassununga, SP, BrazilAs the global population grows, the demand for food and animal-derived products rises significantly, posing a notable challenge to the progress of society in general. Alternative protein production may adequately address such a challenge, and cell-based meat production emerges as a promising solution. This review investigates methodologies for in vitro myogenesis and adipogenesis from stem cells (adult, embryonic, or induced pluripotent stem cells - iPSCs) across different animal species, as well as the remaining challenges for scalability, the possibility of genetic modification, along with safety concerns regarding the commercialization of cell-cultured meat. Regarding such complexities, interdisciplinary approaches will be vital for assessing the potential of cell-cultured meat as a sustainable protein source, mimicking the sensory and nutritional attributes of conventional livestock meat whilst meeting the demands of a growing global population while mitigating environmental impacts.http://www.sciencedirect.com/science/article/pii/S2665927125000103Stem cellsCell-cultured meatCell-based meatAlternative protein
spellingShingle Octavio Bignardi da Silva Nunes
Tiago Willian Buranello
Fabiana de Andrade Farias
Jenyffer Rosero
Kaiana Recchia
Fabiana Fernandes Bressan
Can cell-cultured meat from stem cells pave the way for sustainable alternative protein?
Current Research in Food Science
Stem cells
Cell-cultured meat
Cell-based meat
Alternative protein
title Can cell-cultured meat from stem cells pave the way for sustainable alternative protein?
title_full Can cell-cultured meat from stem cells pave the way for sustainable alternative protein?
title_fullStr Can cell-cultured meat from stem cells pave the way for sustainable alternative protein?
title_full_unstemmed Can cell-cultured meat from stem cells pave the way for sustainable alternative protein?
title_short Can cell-cultured meat from stem cells pave the way for sustainable alternative protein?
title_sort can cell cultured meat from stem cells pave the way for sustainable alternative protein
topic Stem cells
Cell-cultured meat
Cell-based meat
Alternative protein
url http://www.sciencedirect.com/science/article/pii/S2665927125000103
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