Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice

The pathogenicity of S. saprophyticus was studied in mice. A group of white mice were injected transurethrally using a catheter with S. saprophyticus S67 cell suspension in a concentration reached 109 CFU/ml. concomitantly, the role of its peptidoglycan in the pathogenicity was studied by injecting...

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Main Author: Baghdad Science Journal
Format: Article
Language:English
Published: University of Baghdad, College of Science for Women 2007-12-01
Series:مجلة بغداد للعلوم
Online Access:http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/841
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author Baghdad Science Journal
author_facet Baghdad Science Journal
author_sort Baghdad Science Journal
collection DOAJ
description The pathogenicity of S. saprophyticus was studied in mice. A group of white mice were injected transurethrally using a catheter with S. saprophyticus S67 cell suspension in a concentration reached 109 CFU/ml. concomitantly, the role of its peptidoglycan in the pathogenicity was studied by injecting another group of mice with 0.3 mg/0.2 ml of partially purified S. saprophyticus S67 peptidoglycan extract. After autopsy, kidneys and urinary bladder showed several histopathological changes both in cells and peptidoglycan injected mice, included: hydropic degeneration, glomerulus shrinkage, congestion of renal vessels, infiltration of inflammatory cells, and dekeratinization in urinary bladder.
format Article
id doaj-art-74ac286227524b048e11e63640ba4e80
institution Kabale University
issn 2078-8665
2411-7986
language English
publishDate 2007-12-01
publisher University of Baghdad, College of Science for Women
record_format Article
series مجلة بغداد للعلوم
spelling doaj-art-74ac286227524b048e11e63640ba4e802025-08-20T03:57:03ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862007-12-014410.21123/bsj.4.4.597-602Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in miceBaghdad Science JournalThe pathogenicity of S. saprophyticus was studied in mice. A group of white mice were injected transurethrally using a catheter with S. saprophyticus S67 cell suspension in a concentration reached 109 CFU/ml. concomitantly, the role of its peptidoglycan in the pathogenicity was studied by injecting another group of mice with 0.3 mg/0.2 ml of partially purified S. saprophyticus S67 peptidoglycan extract. After autopsy, kidneys and urinary bladder showed several histopathological changes both in cells and peptidoglycan injected mice, included: hydropic degeneration, glomerulus shrinkage, congestion of renal vessels, infiltration of inflammatory cells, and dekeratinization in urinary bladder.http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/841
spellingShingle Baghdad Science Journal
Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
مجلة بغداد للعلوم
title Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
title_full Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
title_fullStr Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
title_full_unstemmed Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
title_short Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice
title_sort role of peptidoglycan in the pathogenesis of staphylococcus saprophyticus in mice
url http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/841
work_keys_str_mv AT baghdadsciencejournal roleofpeptidoglycaninthepathogenesisofstaphylococcussaprophyticusinmice