Bronchoscopic treatment of a giant bronchopleural fistula with autologous platelet-rich plasma

Abstract Background Bronchopleural fistula (BPF) is a severe complication observed in patients undergoing lobectomy or pneumonectomy, often resulting in high morbidity and mortality rates. Case presentation We present a case of successful treatment of a giant bronchopleural fistula (20 mm *10 mm). T...

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Main Authors: Shihu Liu, Yunpeng Xuan, Yongjie Wang, Haiyan Wang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Cardiothoracic Surgery
Online Access:https://doi.org/10.1186/s13019-025-03396-9
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author Shihu Liu
Yunpeng Xuan
Yongjie Wang
Haiyan Wang
author_facet Shihu Liu
Yunpeng Xuan
Yongjie Wang
Haiyan Wang
author_sort Shihu Liu
collection DOAJ
description Abstract Background Bronchopleural fistula (BPF) is a severe complication observed in patients undergoing lobectomy or pneumonectomy, often resulting in high morbidity and mortality rates. Case presentation We present a case of successful treatment of a giant bronchopleural fistula (20 mm *10 mm). The patient underwent a thoracoscopic right lower lobectomy.The approach we used was local injection of autologous frozen platelet-rich plasma (PRP) with bronchoscopic assistance while maintaining digital chest drainage.We chose the treatment of PRP combined with digital drainage for bronchopleural fistula, not only healing of the fistula but also focusing on elimination of the residual cavity in the thoracic cavity. Conclusion This highlights the effectiveness of this comprehensive approach in the treatment of bronchopleural fistulae and provides a promising treatment option for future treatment of similarly large bronchopleural fistulae.
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institution OA Journals
issn 1749-8090
language English
publishDate 2025-04-01
publisher BMC
record_format Article
series Journal of Cardiothoracic Surgery
spelling doaj-art-749a0949eea544a6a98b382f3fb46d9d2025-08-20T02:17:13ZengBMCJournal of Cardiothoracic Surgery1749-80902025-04-012011410.1186/s13019-025-03396-9Bronchoscopic treatment of a giant bronchopleural fistula with autologous platelet-rich plasmaShihu Liu0Yunpeng Xuan1Yongjie Wang2Haiyan Wang3Dept Thorac Surg, Qingdao Univ, Affiliated HospDept Thorac Surg, Qingdao Univ, Affiliated HospDept Thorac Surg, Qingdao Univ, Affiliated HospDepartment of Blood Transfusion, The Affiliated Hospital of Qingdao UniversityAbstract Background Bronchopleural fistula (BPF) is a severe complication observed in patients undergoing lobectomy or pneumonectomy, often resulting in high morbidity and mortality rates. Case presentation We present a case of successful treatment of a giant bronchopleural fistula (20 mm *10 mm). The patient underwent a thoracoscopic right lower lobectomy.The approach we used was local injection of autologous frozen platelet-rich plasma (PRP) with bronchoscopic assistance while maintaining digital chest drainage.We chose the treatment of PRP combined with digital drainage for bronchopleural fistula, not only healing of the fistula but also focusing on elimination of the residual cavity in the thoracic cavity. Conclusion This highlights the effectiveness of this comprehensive approach in the treatment of bronchopleural fistulae and provides a promising treatment option for future treatment of similarly large bronchopleural fistulae.https://doi.org/10.1186/s13019-025-03396-9
spellingShingle Shihu Liu
Yunpeng Xuan
Yongjie Wang
Haiyan Wang
Bronchoscopic treatment of a giant bronchopleural fistula with autologous platelet-rich plasma
Journal of Cardiothoracic Surgery
title Bronchoscopic treatment of a giant bronchopleural fistula with autologous platelet-rich plasma
title_full Bronchoscopic treatment of a giant bronchopleural fistula with autologous platelet-rich plasma
title_fullStr Bronchoscopic treatment of a giant bronchopleural fistula with autologous platelet-rich plasma
title_full_unstemmed Bronchoscopic treatment of a giant bronchopleural fistula with autologous platelet-rich plasma
title_short Bronchoscopic treatment of a giant bronchopleural fistula with autologous platelet-rich plasma
title_sort bronchoscopic treatment of a giant bronchopleural fistula with autologous platelet rich plasma
url https://doi.org/10.1186/s13019-025-03396-9
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AT yunpengxuan bronchoscopictreatmentofagiantbronchopleuralfistulawithautologousplateletrichplasma
AT yongjiewang bronchoscopictreatmentofagiantbronchopleuralfistulawithautologousplateletrichplasma
AT haiyanwang bronchoscopictreatmentofagiantbronchopleuralfistulawithautologousplateletrichplasma