A Study of some biochemical parameters in patients with - thalassemia

Serum levels of iron,copper,ceruloplasmin and transferrine were estimated in three groups of patients with ?- thalassemia: 24 patients have splenectomy thalassemia major, 29 patients have non splenectomy thalassemia major and 19 patients have thalassemia intermedia , data were compared to normal and...

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Bibliographic Details
Main Author: Baghdad Science Journal
Format: Article
Language:English
Published: University of Baghdad, College of Science for Women 2008-09-01
Series:مجلة بغداد للعلوم
Online Access:http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/928
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Summary:Serum levels of iron,copper,ceruloplasmin and transferrine were estimated in three groups of patients with ?- thalassemia: 24 patients have splenectomy thalassemia major, 29 patients have non splenectomy thalassemia major and 19 patients have thalassemia intermedia , data were compared to normal and pathological controls (anemia and minor). There were significant increase in trace element levels in all studied groups of pateints as compared to normal and pathological controls. Also there were a significant increase in ceruloplasmin levels,While the result revealed that there were a significant decrease in transferrine levels in all groups of patients studied as compared to normal and pathological controls. The result also indicate that there is a significant positive correlation between serum ceruloplasmin & copper levels in thalassemia patients while the correlation between serum transferring & iron levels in thalassemia patients are negative.
ISSN:2078-8665
2411-7986