Naturally occurring anti-P1 with high thermal amplitude complicating ABO blood grouping
Anti-P1 is immunoglobulin M type and occurs naturally; it is often detected as a weak- and cold-reactive antibody. However, in rare cases, it is reactive at 37°C or shows hemolytic transfusion reactions. The presence of high thermal amplitude of anti-P1 cannot be ignored and requires cross-match com...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Asian Journal of Transfusion Science |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ajts.ajts_12_21 |
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| author | Shirin Ferdowsi Saeed Mohammadi Moharram Ahmadnezhad Fahimeh Herfat Azita Rezvani Peyman Eshghi Arezoo Oodi |
| author_facet | Shirin Ferdowsi Saeed Mohammadi Moharram Ahmadnezhad Fahimeh Herfat Azita Rezvani Peyman Eshghi Arezoo Oodi |
| author_sort | Shirin Ferdowsi |
| collection | DOAJ |
| description | Anti-P1 is immunoglobulin M type and occurs naturally; it is often detected as a weak- and cold-reactive antibody. However, in rare cases, it is reactive at 37°C or shows hemolytic transfusion reactions. The presence of high thermal amplitude of anti-P1 cannot be ignored and requires cross-match compatible red blood cells for transfusion. In the present study, we report three cases with ABO discrepancy due to anti-P1 that was identified as a cold-reacting antibody with high thermal amplitude. |
| format | Article |
| id | doaj-art-74838f1320e84ff7b81af950b2736607 |
| institution | Kabale University |
| issn | 0973-6247 1998-3565 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Journal of Transfusion Science |
| spelling | doaj-art-74838f1320e84ff7b81af950b27366072025-01-20T09:40:35ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652024-01-0118113513710.4103/ajts.ajts_12_21Naturally occurring anti-P1 with high thermal amplitude complicating ABO blood groupingShirin FerdowsiSaeed MohammadiMoharram AhmadnezhadFahimeh HerfatAzita RezvaniPeyman EshghiArezoo OodiAnti-P1 is immunoglobulin M type and occurs naturally; it is often detected as a weak- and cold-reactive antibody. However, in rare cases, it is reactive at 37°C or shows hemolytic transfusion reactions. The presence of high thermal amplitude of anti-P1 cannot be ignored and requires cross-match compatible red blood cells for transfusion. In the present study, we report three cases with ABO discrepancy due to anti-P1 that was identified as a cold-reacting antibody with high thermal amplitude.https://journals.lww.com/10.4103/ajts.ajts_12_21blood group discrepancycold antibodyhigh thermal amplitude |
| spellingShingle | Shirin Ferdowsi Saeed Mohammadi Moharram Ahmadnezhad Fahimeh Herfat Azita Rezvani Peyman Eshghi Arezoo Oodi Naturally occurring anti-P1 with high thermal amplitude complicating ABO blood grouping Asian Journal of Transfusion Science blood group discrepancy cold antibody high thermal amplitude |
| title | Naturally occurring anti-P1 with high thermal amplitude complicating ABO blood grouping |
| title_full | Naturally occurring anti-P1 with high thermal amplitude complicating ABO blood grouping |
| title_fullStr | Naturally occurring anti-P1 with high thermal amplitude complicating ABO blood grouping |
| title_full_unstemmed | Naturally occurring anti-P1 with high thermal amplitude complicating ABO blood grouping |
| title_short | Naturally occurring anti-P1 with high thermal amplitude complicating ABO blood grouping |
| title_sort | naturally occurring anti p1 with high thermal amplitude complicating abo blood grouping |
| topic | blood group discrepancy cold antibody high thermal amplitude |
| url | https://journals.lww.com/10.4103/ajts.ajts_12_21 |
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