Characterization of Secondary Metabolites in Two Cousinia species

Cousinia is one of the widespread genera of Asteraceae family. According to previous studies on some Cousinia species it was found that these species are rich of triterpenes, sesquiterpenes, flavonoids, acetylenes and steroids. According to our knowledge, there are no published reports on the chemic...

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Main Authors: Leyla Paşayeva, Hanifa Fatullayev, İrem Nur Karakuş, Serap Soylu, Osman Tugay
Format: Article
Language:English
Published: izzet kara 2020-01-01
Series:International Journal of Secondary Metabolite
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Online Access:https://dergipark.org.tr/tr/pub/ijsm/issue/50293/594839?publisher=ijate
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author Leyla Paşayeva
Hanifa Fatullayev
İrem Nur Karakuş
Serap Soylu
Osman Tugay
author_facet Leyla Paşayeva
Hanifa Fatullayev
İrem Nur Karakuş
Serap Soylu
Osman Tugay
author_sort Leyla Paşayeva
collection DOAJ
description Cousinia is one of the widespread genera of Asteraceae family. According to previous studies on some Cousinia species it was found that these species are rich of triterpenes, sesquiterpenes, flavonoids, acetylenes and steroids. According to our knowledge, there are no published reports on the chemical composition of C. iconica Hub. - Mor. and C. aintabensis Boiss. & Hausskn., thus we aimed to investigate secondary metabolites of these species. In this study, the phytochemical constituents of these species were evaluated. Seven of identified compounds were quantified. The quantitative and qualitative determination of compounds within the extracts was carried out by LC-MS/MS.  Phytochemical analyses revealed the presence of flavonoids, saponins, terpenes and steroids. Preliminary examination of the mass spectrums revealed the presence of phenolic acids and derivatives and flavonoid compounds in extracts. According to quantitative analyses the main compound of C. iconica (CI) and C. aintabensis (CA) extracts was rutin with the highest contents (169.779 µg/mgextract and 161.638 µg/mgextract). Moreover, qualitative and quantitative study combined with different biological activities will shed new lights to the advanced studies.
format Article
id doaj-art-747ba3caee5243c29f394da4f190d66c
institution OA Journals
issn 2148-6905
language English
publishDate 2020-01-01
publisher izzet kara
record_format Article
series International Journal of Secondary Metabolite
spelling doaj-art-747ba3caee5243c29f394da4f190d66c2025-08-20T02:13:01Zengizzet karaInternational Journal of Secondary Metabolite2148-69052020-01-016433334110.21448/ijsm.594839618Characterization of Secondary Metabolites in Two Cousinia speciesLeyla Paşayeva0Hanifa Fatullayev1İrem Nur Karakuş2Serap Soylu3Osman TugayERCİYES ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİERCİYES ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİERCİYES ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİERCİYES ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİCousinia is one of the widespread genera of Asteraceae family. According to previous studies on some Cousinia species it was found that these species are rich of triterpenes, sesquiterpenes, flavonoids, acetylenes and steroids. According to our knowledge, there are no published reports on the chemical composition of C. iconica Hub. - Mor. and C. aintabensis Boiss. & Hausskn., thus we aimed to investigate secondary metabolites of these species. In this study, the phytochemical constituents of these species were evaluated. Seven of identified compounds were quantified. The quantitative and qualitative determination of compounds within the extracts was carried out by LC-MS/MS.  Phytochemical analyses revealed the presence of flavonoids, saponins, terpenes and steroids. Preliminary examination of the mass spectrums revealed the presence of phenolic acids and derivatives and flavonoid compounds in extracts. According to quantitative analyses the main compound of C. iconica (CI) and C. aintabensis (CA) extracts was rutin with the highest contents (169.779 µg/mgextract and 161.638 µg/mgextract). Moreover, qualitative and quantitative study combined with different biological activities will shed new lights to the advanced studies.https://dergipark.org.tr/tr/pub/ijsm/issue/50293/594839?publisher=ijatecousiniaasteraceaelc-ms/msrutinflavonoid
spellingShingle Leyla Paşayeva
Hanifa Fatullayev
İrem Nur Karakuş
Serap Soylu
Osman Tugay
Characterization of Secondary Metabolites in Two Cousinia species
International Journal of Secondary Metabolite
cousinia
asteraceae
lc-ms/ms
rutin
flavonoid
title Characterization of Secondary Metabolites in Two Cousinia species
title_full Characterization of Secondary Metabolites in Two Cousinia species
title_fullStr Characterization of Secondary Metabolites in Two Cousinia species
title_full_unstemmed Characterization of Secondary Metabolites in Two Cousinia species
title_short Characterization of Secondary Metabolites in Two Cousinia species
title_sort characterization of secondary metabolites in two cousinia species
topic cousinia
asteraceae
lc-ms/ms
rutin
flavonoid
url https://dergipark.org.tr/tr/pub/ijsm/issue/50293/594839?publisher=ijate
work_keys_str_mv AT leylapasayeva characterizationofsecondarymetabolitesintwocousiniaspecies
AT hanifafatullayev characterizationofsecondarymetabolitesintwocousiniaspecies
AT iremnurkarakus characterizationofsecondarymetabolitesintwocousiniaspecies
AT serapsoylu characterizationofsecondarymetabolitesintwocousiniaspecies
AT osmantugay characterizationofsecondarymetabolitesintwocousiniaspecies