The combination of decitabine with multi-omics confirms the regulatory pattern of the correlation between DNA methylation of the CACNA1C gene and atrial fibrillation

The combination of decitabine with multi-omics confirms the regulatory pattern of the correlation between DNA methylation of the CACNA1C gene and atrial fibrillation

BackgroundStudies have shown that DNA methylation of the CACNA1C gene is involved in the pathogenesis of various diseases and the mechanism of drug action. However, its relationship with atrial fibrillation (AF) remains largely unexplored.ObjectiveTo investigate the association between DNA methylati...

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Bibliographic Details
Main Authors: Yuling Yang, Qijun Li, Xiaoning Liu, Caixia Shao, Heng Yang, Siquan Niu, Hong Peng, Xiangguang Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pharmacology
Subjects:
DNA methylation
calcium voltage-gated channel subunit alpha1 C
decitabine
Pyro-sequencing
atrial fibrillation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1497977/full
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