Autoimmune protocol diet: A personalized elimination diet for patients with autoimmune diseases

The autoimmune protocol diet (AIP) is a personalized elimination diet that aims to determine and exclude the foods that might trigger immune responses, leading to inflammation and symptomatology associated with autoimmune diseases. Focusing on gut health and the importance of the gut microbiome in i...

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Main Authors: Eleni C. Pardali, Arriana Gkouvi, Kalliopi K. Gkouskou, Anastasios C. Manolakis, Christina Tsigalou, Dimitrios G. Goulis, Dimitrios P. Bogdanos, Maria G. Grammatikopoulou
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Metabolism Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589936824000744
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author Eleni C. Pardali
Arriana Gkouvi
Kalliopi K. Gkouskou
Anastasios C. Manolakis
Christina Tsigalou
Dimitrios G. Goulis
Dimitrios P. Bogdanos
Maria G. Grammatikopoulou
author_facet Eleni C. Pardali
Arriana Gkouvi
Kalliopi K. Gkouskou
Anastasios C. Manolakis
Christina Tsigalou
Dimitrios G. Goulis
Dimitrios P. Bogdanos
Maria G. Grammatikopoulou
author_sort Eleni C. Pardali
collection DOAJ
description The autoimmune protocol diet (AIP) is a personalized elimination diet that aims to determine and exclude the foods that might trigger immune responses, leading to inflammation and symptomatology associated with autoimmune diseases. Focusing on gut health and the importance of the gut microbiome in immune regulation and overall well-being, the AIP starts by eliminating foods that might create negative effects on the patients and continues by developing a personalized and tailored diet plan for them. This comprehensive approach aims to mitigate symptoms and improve quality of life of individuals with autoimmune conditions. This review presents and critically appraises current knowledge on the AIP protocol, highlight any oversights, and discuss findings from relevant clinical trials.
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series Metabolism Open
spelling doaj-art-746c8cb5e0a8488485cf97c83b31fbed2025-08-20T02:06:22ZengElsevierMetabolism Open2589-93682025-03-012510034210.1016/j.metop.2024.100342Autoimmune protocol diet: A personalized elimination diet for patients with autoimmune diseasesEleni C. Pardali0Arriana Gkouvi1Kalliopi K. Gkouskou2Anastasios C. Manolakis3Christina Tsigalou4Dimitrios G. Goulis5Dimitrios P. Bogdanos6Maria G. Grammatikopoulou7Unit of Immunonutrition and Clinical Nutrition, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, GreeceUnit of Immunonutrition and Clinical Nutrition, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, GreeceDepartment of Biology, Medical School, National and Kapodistrian University of Athens, Goudi Campus, Athens, Greece; GENOSOPHY P.C., Athens, GreeceDepartment of Gastroenterology, General University Hospital of Larissa, Larissa, GreeceLaboratory of Hygiene and Environmental Protection, Medical School, Democritus University of Thrace, University Hospital, Alexandroupolis, GreeceUnit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, GreeceUnit of Immunonutrition and Clinical Nutrition, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, GreeceUnit of Immunonutrition and Clinical Nutrition, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, Greece; Unit of Reproductive Endocrinology, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece; Corresponding author. Unit of Immunonutrition and Clinical Nutrition, Department of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, Greece.The autoimmune protocol diet (AIP) is a personalized elimination diet that aims to determine and exclude the foods that might trigger immune responses, leading to inflammation and symptomatology associated with autoimmune diseases. Focusing on gut health and the importance of the gut microbiome in immune regulation and overall well-being, the AIP starts by eliminating foods that might create negative effects on the patients and continues by developing a personalized and tailored diet plan for them. This comprehensive approach aims to mitigate symptoms and improve quality of life of individuals with autoimmune conditions. This review presents and critically appraises current knowledge on the AIP protocol, highlight any oversights, and discuss findings from relevant clinical trials.http://www.sciencedirect.com/science/article/pii/S2589936824000744Inflammatory bowel diseaseHashimoto thyroiditisRheumatoid arthritisCeliac diseaseFood allergyIgG
spellingShingle Eleni C. Pardali
Arriana Gkouvi
Kalliopi K. Gkouskou
Anastasios C. Manolakis
Christina Tsigalou
Dimitrios G. Goulis
Dimitrios P. Bogdanos
Maria G. Grammatikopoulou
Autoimmune protocol diet: A personalized elimination diet for patients with autoimmune diseases
Metabolism Open
Inflammatory bowel disease
Hashimoto thyroiditis
Rheumatoid arthritis
Celiac disease
Food allergy
IgG
title Autoimmune protocol diet: A personalized elimination diet for patients with autoimmune diseases
title_full Autoimmune protocol diet: A personalized elimination diet for patients with autoimmune diseases
title_fullStr Autoimmune protocol diet: A personalized elimination diet for patients with autoimmune diseases
title_full_unstemmed Autoimmune protocol diet: A personalized elimination diet for patients with autoimmune diseases
title_short Autoimmune protocol diet: A personalized elimination diet for patients with autoimmune diseases
title_sort autoimmune protocol diet a personalized elimination diet for patients with autoimmune diseases
topic Inflammatory bowel disease
Hashimoto thyroiditis
Rheumatoid arthritis
Celiac disease
Food allergy
IgG
url http://www.sciencedirect.com/science/article/pii/S2589936824000744
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