Oncological Outcomes Following Computer-Aided Reconstructive Jaw Surgery
The purpose of this study was to analyze computer-aided surgical planning (CAS) and margin status following oncological reconstructive surgery of the jaws. A retrospective study was conducted on patients who underwent microvascular reconstructive surgery from 2014 to 2021. The predictor variable was...
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| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Craniomaxillofacial Trauma & Reconstruction |
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| Online Access: | https://www.mdpi.com/1943-3883/18/1/8 |
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| author | John M. Le John Hofheins Myra Rana Jay Ponto Anthony B. Morlandt Yedeh P. Ying |
| author_facet | John M. Le John Hofheins Myra Rana Jay Ponto Anthony B. Morlandt Yedeh P. Ying |
| author_sort | John M. Le |
| collection | DOAJ |
| description | The purpose of this study was to analyze computer-aided surgical planning (CAS) and margin status following oncological reconstructive surgery of the jaws. A retrospective study was conducted on patients who underwent microvascular reconstructive surgery from 2014 to 2021. The predictor variable was the use of CAS. The primary and secondary outcomes were histopathological bone margin status, local recurrence, and disease-free survival (DFS). Covariates included demographic, operative, pathological, and clinical outcomes. Thirty-five CAS and fifty-two non-CAS subjects were included for analysis. Demographic characteristics such as age, sex, and comorbidities were comparable between the study groups, with all <i>p</i>-values > 0.05. For operative variables, the osteocutaneous radial forearm flap was more commonly used in the non-CAS group (34.6%) compared to the CAS group (2.9%) (<i>p</i> < 0.01). The mean follow-up period was shorter in the CAS group (31.9 months) than in the non-CAS group (42.6 months) (<i>p</i> < 0.01). CAS was not associated with margin status (<i>p</i> = 0.65) or local recurrence (<i>p</i> = 0.08). DFS was comparable between the study groups (<i>p</i> = 0.74). Bone margin involvement was not associated with any covariates. The use of CAS in oncological reconstructive jaw surgery was not associated with increased bone margin involvement. |
| format | Article |
| id | doaj-art-7467518953d4423da270732ba2ec0e2a |
| institution | OA Journals |
| issn | 1943-3883 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Craniomaxillofacial Trauma & Reconstruction |
| spelling | doaj-art-7467518953d4423da270732ba2ec0e2a2025-08-20T02:32:57ZengMDPI AGCraniomaxillofacial Trauma & Reconstruction1943-38832025-01-01181810.3390/cmtr18010008Oncological Outcomes Following Computer-Aided Reconstructive Jaw SurgeryJohn M. Le0John Hofheins1Myra Rana2Jay Ponto3Anthony B. Morlandt4Yedeh P. Ying5Department of Oral and Maxillofacial Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USADepartment of Oral and Maxillofacial Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USASchool of Dentistry, University of Alabama at Birmingham, Birmingham, AL 35233, USADepartment of Oral and Maxillofacial Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USADepartment of Oral and Maxillofacial Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USADepartment of Oral and Maxillofacial Surgery, University of Alabama at Birmingham, Birmingham, AL 35233, USAThe purpose of this study was to analyze computer-aided surgical planning (CAS) and margin status following oncological reconstructive surgery of the jaws. A retrospective study was conducted on patients who underwent microvascular reconstructive surgery from 2014 to 2021. The predictor variable was the use of CAS. The primary and secondary outcomes were histopathological bone margin status, local recurrence, and disease-free survival (DFS). Covariates included demographic, operative, pathological, and clinical outcomes. Thirty-five CAS and fifty-two non-CAS subjects were included for analysis. Demographic characteristics such as age, sex, and comorbidities were comparable between the study groups, with all <i>p</i>-values > 0.05. For operative variables, the osteocutaneous radial forearm flap was more commonly used in the non-CAS group (34.6%) compared to the CAS group (2.9%) (<i>p</i> < 0.01). The mean follow-up period was shorter in the CAS group (31.9 months) than in the non-CAS group (42.6 months) (<i>p</i> < 0.01). CAS was not associated with margin status (<i>p</i> = 0.65) or local recurrence (<i>p</i> = 0.08). DFS was comparable between the study groups (<i>p</i> = 0.74). Bone margin involvement was not associated with any covariates. The use of CAS in oncological reconstructive jaw surgery was not associated with increased bone margin involvement.https://www.mdpi.com/1943-3883/18/1/8oral oncologyvirtual surgeryreconstructive surgeryoral cancerlocal recurrence |
| spellingShingle | John M. Le John Hofheins Myra Rana Jay Ponto Anthony B. Morlandt Yedeh P. Ying Oncological Outcomes Following Computer-Aided Reconstructive Jaw Surgery Craniomaxillofacial Trauma & Reconstruction oral oncology virtual surgery reconstructive surgery oral cancer local recurrence |
| title | Oncological Outcomes Following Computer-Aided Reconstructive Jaw Surgery |
| title_full | Oncological Outcomes Following Computer-Aided Reconstructive Jaw Surgery |
| title_fullStr | Oncological Outcomes Following Computer-Aided Reconstructive Jaw Surgery |
| title_full_unstemmed | Oncological Outcomes Following Computer-Aided Reconstructive Jaw Surgery |
| title_short | Oncological Outcomes Following Computer-Aided Reconstructive Jaw Surgery |
| title_sort | oncological outcomes following computer aided reconstructive jaw surgery |
| topic | oral oncology virtual surgery reconstructive surgery oral cancer local recurrence |
| url | https://www.mdpi.com/1943-3883/18/1/8 |
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