Gene duplication and clustering underlie the conservation and diversification of benzylisoquinoline alkaloid biosynthesis in plants

Gene duplication and clustering underlie the conservation and diversification of benzylisoquinoline alkaloid biosynthesis in plants

Abstract Benzylisoquinoline alkaloids (BIAs), comprising ~2500 compounds with pharmacological significance, are well-studied in Ranunculales but poorly understood in Magnoliids, an early-diverging angiosperm group. This study characterizes key enzymes in Houttuynia cordata—including 6-OMT, NMT, CYP8...

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Main Authors: Changheng Shan, Xuan Zhou, Jiaojiao Zhu, Aatif Rashid, Jianhua Wang, Ning An, Changjian Zhang, Wenjuan Ji, Baosong Cai, Ke Wu, Sheng Wang, Zhenhua Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-63175-x
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