The Effects of Endoscopy-Guided Nasojejunal Feeding Tube Placement in Post-COVID-19 ICU Patients: A Retrospective Study

Yuequn Chen, Guiqiong Wu, Chaojun Qu, Zimao Ye, Yihao Kang, Xin Tian Department of Intensive Care Unit, Fifth Affiliated Hospital of Wenzhou Medical University; Lishui Municipal Central Hospital, Lishui, 323000, People’s Republic of ChinaCorrespondence: Xin Tian, Department of Intensive care unit, F...

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Main Authors: Chen Y, Wu G, Qu C, Ye Z, Kang Y, Tian X
Format: Article
Language:English
Published: Dove Medical Press 2025-07-01
Series:International Journal of General Medicine
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Online Access:https://www.dovepress.com/the-effects-of-endoscopy-guided-nasojejunal-feeding-tube-placement-in--peer-reviewed-fulltext-article-IJGM
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author Chen Y
Wu G
Qu C
Ye Z
Kang Y
Tian X
author_facet Chen Y
Wu G
Qu C
Ye Z
Kang Y
Tian X
author_sort Chen Y
collection DOAJ
description Yuequn Chen, Guiqiong Wu, Chaojun Qu, Zimao Ye, Yihao Kang, Xin Tian Department of Intensive Care Unit, Fifth Affiliated Hospital of Wenzhou Medical University; Lishui Municipal Central Hospital, Lishui, 323000, People’s Republic of ChinaCorrespondence: Xin Tian, Department of Intensive care unit, Fifth Affiliated Hospital of Wenzhou Medical University; Lishui Municipal Central Hospital, No. 289, Kuocang Road, Liandu District, Lishui, 323000, People’s Republic of China, Tel +86-0578-2285301, Email zjlstx@126.comBackground: The impact of complications and long-term outcomes remains unclear for endoscopy-guided nasojejunal feeding tube (ENFT) placement versus blind nasogastric feeding tube (BNFT) placement on post-COVID-19 ICU patients.Study Design: A retrospective cohort study comparing BNFT and ENFT placement in ICU patients post-COVID-19 infection.Objective: To evaluate the impact of BNFT versus ENFT placement methods on complications in post-COVID-19 ICU patients requiring enteral feeding.Participants: A total of 310 ICU patients were retrospectively analyzed after applying inclusion and exclusion criteria, comprising 99 patients in the ENFT group and 211 patients in the BNFT group.Setting: The study was conducted in the intensive care units of a tertiary care hospital from September 2023 to November 2023.Outcome Measures: Primary outcomes included baseline clinical characteristics and symptoms prior to COVID-19 infection. Secondary outcomes assessed post-COVID-19 complications over short (up to 2 weeks), medium (2– 4 weeks), and long-term (beyond 4 weeks) periods. These complications included shortness of breath, cognitive dysfunction, muscle and joint pain, sleep disturbances, and gastrointestinal symptoms, measured by GSRS and SAQ scores.Results: Baseline characteristics were similar between both groups (p > 0.05), indicating well-matched cohorts. Post-COVID-19, the ENFT group exhibited significantly lower rates of shortness of breath, cognitive dysfunction, muscle and joint pain, sleep disturbances, and mental health challenges, especially for long-term feeding tube usage (p < 0.05). GSRS scores were lower and SAQ scores were higher in the ENFT group, indicating better gastrointestinal and cardiovascular outcomes.Conclusion: ENFT placement is associated with fewer post-COVID-19 complications compared to BNFT, particularly for patients requiring long-term feeding tube usage in the ICU.Keywords: nasojejunal tube placement, prone ventilation, post-COVID-19 ICU patients, safety, enteral feeding
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spelling doaj-art-74566eefe2124dff8b8dd1d067a8678f2025-08-20T03:31:16ZengDove Medical PressInternational Journal of General Medicine1178-70742025-07-01Volume 18Issue 136093626104405The Effects of Endoscopy-Guided Nasojejunal Feeding Tube Placement in Post-COVID-19 ICU Patients: A Retrospective StudyChen YWu GQu C0Ye ZKang YTian XICUYuequn Chen, Guiqiong Wu, Chaojun Qu, Zimao Ye, Yihao Kang, Xin Tian Department of Intensive Care Unit, Fifth Affiliated Hospital of Wenzhou Medical University; Lishui Municipal Central Hospital, Lishui, 323000, People’s Republic of ChinaCorrespondence: Xin Tian, Department of Intensive care unit, Fifth Affiliated Hospital of Wenzhou Medical University; Lishui Municipal Central Hospital, No. 289, Kuocang Road, Liandu District, Lishui, 323000, People’s Republic of China, Tel +86-0578-2285301, Email zjlstx@126.comBackground: The impact of complications and long-term outcomes remains unclear for endoscopy-guided nasojejunal feeding tube (ENFT) placement versus blind nasogastric feeding tube (BNFT) placement on post-COVID-19 ICU patients.Study Design: A retrospective cohort study comparing BNFT and ENFT placement in ICU patients post-COVID-19 infection.Objective: To evaluate the impact of BNFT versus ENFT placement methods on complications in post-COVID-19 ICU patients requiring enteral feeding.Participants: A total of 310 ICU patients were retrospectively analyzed after applying inclusion and exclusion criteria, comprising 99 patients in the ENFT group and 211 patients in the BNFT group.Setting: The study was conducted in the intensive care units of a tertiary care hospital from September 2023 to November 2023.Outcome Measures: Primary outcomes included baseline clinical characteristics and symptoms prior to COVID-19 infection. Secondary outcomes assessed post-COVID-19 complications over short (up to 2 weeks), medium (2– 4 weeks), and long-term (beyond 4 weeks) periods. These complications included shortness of breath, cognitive dysfunction, muscle and joint pain, sleep disturbances, and gastrointestinal symptoms, measured by GSRS and SAQ scores.Results: Baseline characteristics were similar between both groups (p > 0.05), indicating well-matched cohorts. Post-COVID-19, the ENFT group exhibited significantly lower rates of shortness of breath, cognitive dysfunction, muscle and joint pain, sleep disturbances, and mental health challenges, especially for long-term feeding tube usage (p < 0.05). GSRS scores were lower and SAQ scores were higher in the ENFT group, indicating better gastrointestinal and cardiovascular outcomes.Conclusion: ENFT placement is associated with fewer post-COVID-19 complications compared to BNFT, particularly for patients requiring long-term feeding tube usage in the ICU.Keywords: nasojejunal tube placement, prone ventilation, post-COVID-19 ICU patients, safety, enteral feedinghttps://www.dovepress.com/the-effects-of-endoscopy-guided-nasojejunal-feeding-tube-placement-in--peer-reviewed-fulltext-article-IJGMNasojejunal tube placementProne ventilationPost-COVID-19 ICU patientsSafetyEnteral feeding.
spellingShingle Chen Y
Wu G
Qu C
Ye Z
Kang Y
Tian X
The Effects of Endoscopy-Guided Nasojejunal Feeding Tube Placement in Post-COVID-19 ICU Patients: A Retrospective Study
International Journal of General Medicine
Nasojejunal tube placement
Prone ventilation
Post-COVID-19 ICU patients
Safety
Enteral feeding.
title The Effects of Endoscopy-Guided Nasojejunal Feeding Tube Placement in Post-COVID-19 ICU Patients: A Retrospective Study
title_full The Effects of Endoscopy-Guided Nasojejunal Feeding Tube Placement in Post-COVID-19 ICU Patients: A Retrospective Study
title_fullStr The Effects of Endoscopy-Guided Nasojejunal Feeding Tube Placement in Post-COVID-19 ICU Patients: A Retrospective Study
title_full_unstemmed The Effects of Endoscopy-Guided Nasojejunal Feeding Tube Placement in Post-COVID-19 ICU Patients: A Retrospective Study
title_short The Effects of Endoscopy-Guided Nasojejunal Feeding Tube Placement in Post-COVID-19 ICU Patients: A Retrospective Study
title_sort effects of endoscopy guided nasojejunal feeding tube placement in post covid 19 icu patients a retrospective study
topic Nasojejunal tube placement
Prone ventilation
Post-COVID-19 ICU patients
Safety
Enteral feeding.
url https://www.dovepress.com/the-effects-of-endoscopy-guided-nasojejunal-feeding-tube-placement-in--peer-reviewed-fulltext-article-IJGM
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