Hypercholesterolemia and the role of lipid metabolism gene CES1 in immune infiltration promote central nervous system relapse in acute myeloid leukemia

Hypercholesterolemia and the role of lipid metabolism gene CES1 in immune infiltration promote central nervous system relapse in acute myeloid leukemia

BackgroundAlterations in multiple lipid metabolism pathways are associated with cancer progression. However, the relationship between lipid metabolism and central nervous system (CNS) relapse in acute myeloid leukemia (AML) remains unclear.MethodsWe conducted a retrospective analysis of 806 AML case...

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Bibliographic Details
Main Authors: Wanwan Bao, Yansong Tu, Shan Zhang, Xiaoyan Jiang, Huijun Chen, Huaijun Tu, Jian Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
central nervous system leukemia
hyperlipidemia
CES1
tumor microenvironment
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1575472/full
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