Recurrence of Rosacea Induced by Compound Vitamin Tablets: A Case Report

Hui-Shang Feng,1,2 Wan-Tong Zhang,3 Zi-Ye Xi,1 Guo-Dong Hua,4 Chun-Miao Xue,4 Ling-Ling Li,1 Shuang-Qing Qu,1 Li-Li Zhao,1 Tai Zhang,4 Bao-Chen Zhu,4 Yuan-Wen Li5 1Department of Dermatology, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Second Clin...

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Main Authors: Feng HS, Zhang WT, Xi ZY, Hua GD, Xue CM, Li LL, Qu SQ, Zhao LL, Zhang T, Zhu BC, Li YW
Format: Article
Language:English
Published: Dove Medical Press 2025-03-01
Series:Journal of Inflammation Research
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Online Access:https://www.dovepress.com/recurrence-of-rosacea-induced-by-compound-vitamin-tablets-a-case-repor-peer-reviewed-fulltext-article-JIR
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author Feng HS
Zhang WT
Xi ZY
Hua GD
Xue CM
Li LL
Qu SQ
Zhao LL
Zhang T
Zhu BC
Li YW
author_facet Feng HS
Zhang WT
Xi ZY
Hua GD
Xue CM
Li LL
Qu SQ
Zhao LL
Zhang T
Zhu BC
Li YW
author_sort Feng HS
collection DOAJ
description Hui-Shang Feng,1,2 Wan-Tong Zhang,3 Zi-Ye Xi,1 Guo-Dong Hua,4 Chun-Miao Xue,4 Ling-Ling Li,1 Shuang-Qing Qu,1 Li-Li Zhao,1 Tai Zhang,4 Bao-Chen Zhu,4 Yuan-Wen Li5 1Department of Dermatology, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Second Clinical Medical School, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 3Institute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of China; 4Department of Pharmacy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 5Department of Dermatology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of ChinaCorrespondence: Bao-Chen Zhu, Department of Pharmacy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Hai Yun Cang on the 5th Zip Dongcheng District, Beijing, 100700, People’s Republic of China, Email zbcbock123@sina.com Yuan-Wen Li, Department of Dermatology, Dongfang Hospital Beijing University of Chinese Medicine, No. 6 Fangxingyuan Fengtai District, Beijing, 100078, People’s Republic of China, Email 15810104902@163.comAbstract: We present a case of rosacea recurrence in a 37-year-old woman associated with the intake of compound vitamin tablets during the preconception period, with a Naranjo score of 7. These tablets, commonly used for nutritional supplementation to prevent anemia, contain a variety of vitamins, minerals, and trace elements. Despite their widespread use, reports of such supplements causing rosacea recurrence are rare. In this case, the patient experienced a recurrence of facial redness, stinging, and burning after taking the tablets on two separate occasions. Skin dermatoscopy, VISIA imaging, Clinician’s Erythema Assessment (CEA), Investigator’s Global Assessment (IGA), and Visual Analogue Scale (VAS) all confirmed the recurrence of rosacea. Given her intention to conceive, symptomatic treatment with emollient and reparative dressings was administered. The patient’s symptoms gradually resolved after discontinuing the medication, with no recurrence observed during follow-up visits. Women with a history of rosacea should avoid these tablets during preconception, pregnancy, and lactation to prevent recurrence and should choose supplements carefully to minimize the risk of rosacea flare-ups.Keywords: compound vitamin tablets, rosacea, drug adverse reaction, women of childbearing age, immune inflammatory dermatosis
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series Journal of Inflammation Research
spelling doaj-art-743b91e5185a4387bb38ecb63fa3a0c02025-08-20T03:02:07ZengDove Medical PressJournal of Inflammation Research1178-70312025-03-01Volume 1833113319100874Recurrence of Rosacea Induced by Compound Vitamin Tablets: A Case ReportFeng HSZhang WTXi ZYHua GDXue CMLi LLQu SQZhao LLZhang TZhu BCLi YWHui-Shang Feng,1,2 Wan-Tong Zhang,3 Zi-Ye Xi,1 Guo-Dong Hua,4 Chun-Miao Xue,4 Ling-Ling Li,1 Shuang-Qing Qu,1 Li-Li Zhao,1 Tai Zhang,4 Bao-Chen Zhu,4 Yuan-Wen Li5 1Department of Dermatology, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2Second Clinical Medical School, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 3Institute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of China; 4Department of Pharmacy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 5Department of Dermatology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of ChinaCorrespondence: Bao-Chen Zhu, Department of Pharmacy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Hai Yun Cang on the 5th Zip Dongcheng District, Beijing, 100700, People’s Republic of China, Email zbcbock123@sina.com Yuan-Wen Li, Department of Dermatology, Dongfang Hospital Beijing University of Chinese Medicine, No. 6 Fangxingyuan Fengtai District, Beijing, 100078, People’s Republic of China, Email 15810104902@163.comAbstract: We present a case of rosacea recurrence in a 37-year-old woman associated with the intake of compound vitamin tablets during the preconception period, with a Naranjo score of 7. These tablets, commonly used for nutritional supplementation to prevent anemia, contain a variety of vitamins, minerals, and trace elements. Despite their widespread use, reports of such supplements causing rosacea recurrence are rare. In this case, the patient experienced a recurrence of facial redness, stinging, and burning after taking the tablets on two separate occasions. Skin dermatoscopy, VISIA imaging, Clinician’s Erythema Assessment (CEA), Investigator’s Global Assessment (IGA), and Visual Analogue Scale (VAS) all confirmed the recurrence of rosacea. Given her intention to conceive, symptomatic treatment with emollient and reparative dressings was administered. The patient’s symptoms gradually resolved after discontinuing the medication, with no recurrence observed during follow-up visits. Women with a history of rosacea should avoid these tablets during preconception, pregnancy, and lactation to prevent recurrence and should choose supplements carefully to minimize the risk of rosacea flare-ups.Keywords: compound vitamin tablets, rosacea, drug adverse reaction, women of childbearing age, immune inflammatory dermatosishttps://www.dovepress.com/recurrence-of-rosacea-induced-by-compound-vitamin-tablets-a-case-repor-peer-reviewed-fulltext-article-JIRcompound vitamin tabletsrosaceadrug adverse reactionwomen of childbearing ageimmune inflammatory dermatosis
spellingShingle Feng HS
Zhang WT
Xi ZY
Hua GD
Xue CM
Li LL
Qu SQ
Zhao LL
Zhang T
Zhu BC
Li YW
Recurrence of Rosacea Induced by Compound Vitamin Tablets: A Case Report
Journal of Inflammation Research
compound vitamin tablets
rosacea
drug adverse reaction
women of childbearing age
immune inflammatory dermatosis
title Recurrence of Rosacea Induced by Compound Vitamin Tablets: A Case Report
title_full Recurrence of Rosacea Induced by Compound Vitamin Tablets: A Case Report
title_fullStr Recurrence of Rosacea Induced by Compound Vitamin Tablets: A Case Report
title_full_unstemmed Recurrence of Rosacea Induced by Compound Vitamin Tablets: A Case Report
title_short Recurrence of Rosacea Induced by Compound Vitamin Tablets: A Case Report
title_sort recurrence of rosacea induced by compound vitamin tablets a case report
topic compound vitamin tablets
rosacea
drug adverse reaction
women of childbearing age
immune inflammatory dermatosis
url https://www.dovepress.com/recurrence-of-rosacea-induced-by-compound-vitamin-tablets-a-case-repor-peer-reviewed-fulltext-article-JIR
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