Nutrition and Aging Biology: Summary of a Research Centers Collaborative Network Workshop and Research Needs

As the global population of older adults increases, identifying strategies that modify biological aging has become an increasing priority for improving health span and lifespan. When coupled with the growing epidemic of overweight and obesity, nutritional strategies have garnered considerable resear...

Full description

Saved in:
Bibliographic Details
Main Authors: M Kyla Shea, S Delanie Lynch, Tina E Brinkley, Stephen B Kritchevsky
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Current Developments in Nutrition
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2475299125029464
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849252169263349760
author M Kyla Shea
S Delanie Lynch
Tina E Brinkley
Stephen B Kritchevsky
author_facet M Kyla Shea
S Delanie Lynch
Tina E Brinkley
Stephen B Kritchevsky
author_sort M Kyla Shea
collection DOAJ
description As the global population of older adults increases, identifying strategies that modify biological aging has become an increasing priority for improving health span and lifespan. When coupled with the growing epidemic of overweight and obesity, nutritional strategies have garnered considerable research attention due to their potential to modulate both aging and metabolism at the cellular and molecular levels. Several key nutritional influences are currently being studied for their effects on aging biology, including caloric restriction, protein restriction, time-restricted eating, ketosis, and the gut microbiome. Of particular relevance is the role of dietary interventions in older adults with obesity, which must carefully balance the cardiometabolic benefits of weight loss with the unintended musculoskeletal losses, including muscle and bone mass. To discuss these critical issues, the Research Centers Collaborative Network sponsored a 1.5-d multidisciplinary workshop bringing together basic, clinical, and translational scientists in the fields of nutrition and aging biology. This meeting included sessions on calorie and protein restriction, timing of food intake, the gut microbiome, and obesity treatment for older adults. The agenda and recordings are archived at https://www.rccn-aging.org/nutrition-and-aging-biology. In this article, we describe the workshop’s themes and discussions and highlight research gaps that, if filled, will considerably advance our understanding of the role of nutrition in healthy aging.
format Article
id doaj-art-7422877525894d53b71c1e9e5ba0cc4e
institution Kabale University
issn 2475-2991
language English
publishDate 2025-07-01
publisher Elsevier
record_format Article
series Current Developments in Nutrition
spelling doaj-art-7422877525894d53b71c1e9e5ba0cc4e2025-08-20T03:56:42ZengElsevierCurrent Developments in Nutrition2475-29912025-07-019710748510.1016/j.cdnut.2025.107485Nutrition and Aging Biology: Summary of a Research Centers Collaborative Network Workshop and Research NeedsM Kyla Shea0S Delanie Lynch1Tina E Brinkley2Stephen B Kritchevsky3USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, United States; Corresponding author.Center for Injury Biomechanics, Wake Forest University School of Medicine, Winston-Salem, NC, United StatesSticht Center for Healthy Aging and Alzheimer’s Prevention, Wake Forest University School of Medicine, Winston-Salem, NC, United StatesSticht Center for Healthy Aging and Alzheimer’s Prevention, Wake Forest University School of Medicine, Winston-Salem, NC, United StatesAs the global population of older adults increases, identifying strategies that modify biological aging has become an increasing priority for improving health span and lifespan. When coupled with the growing epidemic of overweight and obesity, nutritional strategies have garnered considerable research attention due to their potential to modulate both aging and metabolism at the cellular and molecular levels. Several key nutritional influences are currently being studied for their effects on aging biology, including caloric restriction, protein restriction, time-restricted eating, ketosis, and the gut microbiome. Of particular relevance is the role of dietary interventions in older adults with obesity, which must carefully balance the cardiometabolic benefits of weight loss with the unintended musculoskeletal losses, including muscle and bone mass. To discuss these critical issues, the Research Centers Collaborative Network sponsored a 1.5-d multidisciplinary workshop bringing together basic, clinical, and translational scientists in the fields of nutrition and aging biology. This meeting included sessions on calorie and protein restriction, timing of food intake, the gut microbiome, and obesity treatment for older adults. The agenda and recordings are archived at https://www.rccn-aging.org/nutrition-and-aging-biology. In this article, we describe the workshop’s themes and discussions and highlight research gaps that, if filled, will considerably advance our understanding of the role of nutrition in healthy aging.http://www.sciencedirect.com/science/article/pii/S2475299125029464older adultsagingaging biologyobesitycaloric restrictionnutrition
spellingShingle M Kyla Shea
S Delanie Lynch
Tina E Brinkley
Stephen B Kritchevsky
Nutrition and Aging Biology: Summary of a Research Centers Collaborative Network Workshop and Research Needs
Current Developments in Nutrition
older adults
aging
aging biology
obesity
caloric restriction
nutrition
title Nutrition and Aging Biology: Summary of a Research Centers Collaborative Network Workshop and Research Needs
title_full Nutrition and Aging Biology: Summary of a Research Centers Collaborative Network Workshop and Research Needs
title_fullStr Nutrition and Aging Biology: Summary of a Research Centers Collaborative Network Workshop and Research Needs
title_full_unstemmed Nutrition and Aging Biology: Summary of a Research Centers Collaborative Network Workshop and Research Needs
title_short Nutrition and Aging Biology: Summary of a Research Centers Collaborative Network Workshop and Research Needs
title_sort nutrition and aging biology summary of a research centers collaborative network workshop and research needs
topic older adults
aging
aging biology
obesity
caloric restriction
nutrition
url http://www.sciencedirect.com/science/article/pii/S2475299125029464
work_keys_str_mv AT mkylashea nutritionandagingbiologysummaryofaresearchcenterscollaborativenetworkworkshopandresearchneeds
AT sdelanielynch nutritionandagingbiologysummaryofaresearchcenterscollaborativenetworkworkshopandresearchneeds
AT tinaebrinkley nutritionandagingbiologysummaryofaresearchcenterscollaborativenetworkworkshopandresearchneeds
AT stephenbkritchevsky nutritionandagingbiologysummaryofaresearchcenterscollaborativenetworkworkshopandresearchneeds