A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer

Necrotizing autoimmune myopathy (NAM) is a rare subgroup of idiopathic inflammatory myopathies (IIM). This pathology usually affects proximal limb muscles and in some cases the myocardium. Patients usually display proximal limb weakness. Muscular biopsy is required to confirm the diagnosis. We repor...

Full description

Saved in:
Bibliographic Details
Main Authors: Simon Ponthus, Omar Kherad, Nicole Petriccioli, Johannes Alexander Lobrinus, Pierre-André A. Guerne
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2017/1891897
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Necrotizing autoimmune myopathy (NAM) is a rare subgroup of idiopathic inflammatory myopathies (IIM). This pathology usually affects proximal limb muscles and in some cases the myocardium. Patients usually display proximal limb weakness. Muscular biopsy is required to confirm the diagnosis. We report the case of a 64-year-old woman with an atypical first presentation of NAM, manifested by chest pain in the context of metastatic endometrial cancer. The diagnosis of NAM was however made when she returned a second time with proximal limb weakness. A treatment with prednisone was then initiated, to which rituximab was rapidly associated, beside a specific chemotherapy.
ISSN:2090-6889
2090-6897