Positron emission tomography-magnetic resonance liver parenchyma attenuation correction artifact in secondary hemochromatosis

Positron emission tomography-magnetic resonance (PET-MR) hybrid imaging is a relatively new imaging modality combining the superb MR contrast capabilities among different soft-tissue structures with the high sensitivity of PET functional imaging. With the development of any new technology, a variety...

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Main Authors: Robert Matthews, Michael Joseph Salerno, Paul Vaska, Halley Hindman
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-01-01
Series:World Journal of Nuclear Medicine
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_10_19
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author Robert Matthews
Michael Joseph Salerno
Paul Vaska
Halley Hindman
author_facet Robert Matthews
Michael Joseph Salerno
Paul Vaska
Halley Hindman
author_sort Robert Matthews
collection DOAJ
description Positron emission tomography-magnetic resonance (PET-MR) hybrid imaging is a relatively new imaging modality combining the superb MR contrast capabilities among different soft-tissue structures with the high sensitivity of PET functional imaging. With the development of any new technology, a variety of limitations will be encountered including the introduction of new types of artifacts. In this case report, we present a restaging PET-MR scan for multiple myeloma that showed severely decreased fluorodeoxyglucose activity in the liver on the PET attenuated corrected images. Careful analysis showed the cause of the decreased activity to be the improper density assignment on the mu map caused by iron deposition within the liver. Follow-up imaging showed reversal of the phenomena following improvement of liver disease.
format Article
id doaj-art-740b706d29d845e8a82e57535fc0980f
institution OA Journals
issn 1450-1147
1607-3312
language English
publishDate 2020-01-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series World Journal of Nuclear Medicine
spelling doaj-art-740b706d29d845e8a82e57535fc0980f2025-08-20T01:57:45ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122020-01-011901858810.4103/wjnm.WJNM_10_19Positron emission tomography-magnetic resonance liver parenchyma attenuation correction artifact in secondary hemochromatosisRobert Matthews0Michael Joseph Salerno1Paul Vaska2Halley Hindman3Department of Radiology, Stony Brook University Hospital, NY, USADepartment of Biomedical Engineering, Stony Brook University, NY, USADepartment of Biomedical Engineering, Stony Brook University, NY, USADepartment of Radiology, Stony Brook University Hospital, NY, USAPositron emission tomography-magnetic resonance (PET-MR) hybrid imaging is a relatively new imaging modality combining the superb MR contrast capabilities among different soft-tissue structures with the high sensitivity of PET functional imaging. With the development of any new technology, a variety of limitations will be encountered including the introduction of new types of artifacts. In this case report, we present a restaging PET-MR scan for multiple myeloma that showed severely decreased fluorodeoxyglucose activity in the liver on the PET attenuated corrected images. Careful analysis showed the cause of the decreased activity to be the improper density assignment on the mu map caused by iron deposition within the liver. Follow-up imaging showed reversal of the phenomena following improvement of liver disease.http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_10_19attenuation correctionfluorodeoxyglucosemu mapmultiple myelomapositron emission tomography-magnetic resonance
spellingShingle Robert Matthews
Michael Joseph Salerno
Paul Vaska
Halley Hindman
Positron emission tomography-magnetic resonance liver parenchyma attenuation correction artifact in secondary hemochromatosis
World Journal of Nuclear Medicine
attenuation correction
fluorodeoxyglucose
mu map
multiple myeloma
positron emission tomography-magnetic resonance
title Positron emission tomography-magnetic resonance liver parenchyma attenuation correction artifact in secondary hemochromatosis
title_full Positron emission tomography-magnetic resonance liver parenchyma attenuation correction artifact in secondary hemochromatosis
title_fullStr Positron emission tomography-magnetic resonance liver parenchyma attenuation correction artifact in secondary hemochromatosis
title_full_unstemmed Positron emission tomography-magnetic resonance liver parenchyma attenuation correction artifact in secondary hemochromatosis
title_short Positron emission tomography-magnetic resonance liver parenchyma attenuation correction artifact in secondary hemochromatosis
title_sort positron emission tomography magnetic resonance liver parenchyma attenuation correction artifact in secondary hemochromatosis
topic attenuation correction
fluorodeoxyglucose
mu map
multiple myeloma
positron emission tomography-magnetic resonance
url http://www.thieme-connect.de/DOI/DOI?10.4103/wjnm.WJNM_10_19
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AT michaeljosephsalerno positronemissiontomographymagneticresonanceliverparenchymaattenuationcorrectionartifactinsecondaryhemochromatosis
AT paulvaska positronemissiontomographymagneticresonanceliverparenchymaattenuationcorrectionartifactinsecondaryhemochromatosis
AT halleyhindman positronemissiontomographymagneticresonanceliverparenchymaattenuationcorrectionartifactinsecondaryhemochromatosis