Regenerative Cartilage Treatment for Focal Chondral Defects in the Knee: Focus on Marrow-Stimulating and Cell-Based Scaffold Approaches

Regenerative Cartilage Treatment for Focal Chondral Defects in the Knee: Focus on Marrow-Stimulating and Cell-Based Scaffold Approaches

Focal chondral defects of the knee are a common cause of pain and functional limitation in active individuals and may predispose to early degenerative joint changes. Given the limited regenerative capacity of hyaline cartilage, biologically based surgical strategies have emerged to promote tissue re...

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Bibliographic Details
Main Authors: Filippo Migliorini, Francesco Simeone, Tommaso Bardazzi, Michael Kurt Memminger, Gennaro Pipino, Raju Vaishya, Nicola Maffulli
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Series:Cells
Subjects:
chondral
cartilage
surgery
cell-based therapy
regenerative medicine
Online Access:https://www.mdpi.com/2073-4409/14/15/1217
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