Comparison between Carotid Artery Wall Thickness Measured by Multidetector Row Computed Tomography Angiography and Intimae-Media Thickness Measured by Sonography
The increased thickness of the carotid wall >1 mm is a significant predictor of coronary and cerebrovascular diseases. The purpose of our study was to assess the agreement between multidetector row computed tomography angiography (MDCTA) in measuring carotid artery wall thickness (CAWT) and color...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2011.147 |
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| author | Živorad N. Savić Ivan I. Soldatović Milan D. Brajović Aleksandra M. Pavlović Dušan R. Mladenović Vesna D. Škodrić-Trifunović |
| author_facet | Živorad N. Savić Ivan I. Soldatović Milan D. Brajović Aleksandra M. Pavlović Dušan R. Mladenović Vesna D. Škodrić-Trifunović |
| author_sort | Živorad N. Savić |
| collection | DOAJ |
| description | The increased thickness of the carotid wall >1 mm is a significant predictor of coronary and cerebrovascular diseases. The purpose of our study was to assess the agreement between multidetector row computed tomography angiography (MDCTA) in measuring carotid artery wall thickness (CAWT) and color Doppler ultrasound (CD-US) in measuring intimae-media thickness (IMT). Eighty-nine patients (aged 35–81) were prospectively analyzed using a 64-detector MDCTA and a CD-US scanner. Continuous data were described as the mean value ± standard deviation, and were compared using the Mann–Whitney U test. A p value <0.05 was considered significant. Bland–Altman statistics were employed to measure the agreement between MDCTA and CD-US. CAWT ranged from 0.62 to 1.60 mm, with a mean value of 1.09 mm. IMT ranged from 0.60 to 1.55 mm, with a mean value of 1.06 mm. We observed an excellent agreement between CD-US and MDCTA in the evaluation of the common carotid artery thickness, with a bias between methods of 0.029 mm (which is a highly statistically important difference of absolute values [t = 43.289; p < 0.01] obtained by paired T test), and limits of agreement from 0.04 to 0.104. Pearson correlation coefficient was 0.9997 (95% CI 0.9996–0.9998; p < 0.01). We conclude that there is an excellent correlation between CAWT and IMT measurements obtained with the MDCTA and CD-US. |
| format | Article |
| id | doaj-art-73ebd13ef6384804802c54513b55db75 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-73ebd13ef6384804802c54513b55db752025-02-03T01:21:19ZengWileyThe Scientific World Journal1537-744X2011-01-01111582159010.1100/tsw.2011.147Comparison between Carotid Artery Wall Thickness Measured by Multidetector Row Computed Tomography Angiography and Intimae-Media Thickness Measured by SonographyŽivorad N. Savić0Ivan I. Soldatović1Milan D. Brajović2Aleksandra M. Pavlović3Dušan R. Mladenović4Vesna D. Škodrić-Trifunović5Center of Radiology and Magnetic Resonance, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, SerbiaInstitute of Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, SerbiaClinical Center Zvezdara, Department of Cardiology, Belgrade, SerbiaClinic for Neurology, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, SerbiaInstitute of Pathophysiology, Faculty of Medicine, University of Belgrade, SerbiaClinic for Lung Diseases, Clinical Center of Serbia, Belgrade, Medical School, University of Belgrade, SerbiaThe increased thickness of the carotid wall >1 mm is a significant predictor of coronary and cerebrovascular diseases. The purpose of our study was to assess the agreement between multidetector row computed tomography angiography (MDCTA) in measuring carotid artery wall thickness (CAWT) and color Doppler ultrasound (CD-US) in measuring intimae-media thickness (IMT). Eighty-nine patients (aged 35–81) were prospectively analyzed using a 64-detector MDCTA and a CD-US scanner. Continuous data were described as the mean value ± standard deviation, and were compared using the Mann–Whitney U test. A p value <0.05 was considered significant. Bland–Altman statistics were employed to measure the agreement between MDCTA and CD-US. CAWT ranged from 0.62 to 1.60 mm, with a mean value of 1.09 mm. IMT ranged from 0.60 to 1.55 mm, with a mean value of 1.06 mm. We observed an excellent agreement between CD-US and MDCTA in the evaluation of the common carotid artery thickness, with a bias between methods of 0.029 mm (which is a highly statistically important difference of absolute values [t = 43.289; p < 0.01] obtained by paired T test), and limits of agreement from 0.04 to 0.104. Pearson correlation coefficient was 0.9997 (95% CI 0.9996–0.9998; p < 0.01). We conclude that there is an excellent correlation between CAWT and IMT measurements obtained with the MDCTA and CD-US.http://dx.doi.org/10.1100/tsw.2011.147 |
| spellingShingle | Živorad N. Savić Ivan I. Soldatović Milan D. Brajović Aleksandra M. Pavlović Dušan R. Mladenović Vesna D. Škodrić-Trifunović Comparison between Carotid Artery Wall Thickness Measured by Multidetector Row Computed Tomography Angiography and Intimae-Media Thickness Measured by Sonography The Scientific World Journal |
| title | Comparison between Carotid Artery Wall Thickness Measured by Multidetector Row Computed Tomography Angiography and Intimae-Media Thickness Measured by Sonography |
| title_full | Comparison between Carotid Artery Wall Thickness Measured by Multidetector Row Computed Tomography Angiography and Intimae-Media Thickness Measured by Sonography |
| title_fullStr | Comparison between Carotid Artery Wall Thickness Measured by Multidetector Row Computed Tomography Angiography and Intimae-Media Thickness Measured by Sonography |
| title_full_unstemmed | Comparison between Carotid Artery Wall Thickness Measured by Multidetector Row Computed Tomography Angiography and Intimae-Media Thickness Measured by Sonography |
| title_short | Comparison between Carotid Artery Wall Thickness Measured by Multidetector Row Computed Tomography Angiography and Intimae-Media Thickness Measured by Sonography |
| title_sort | comparison between carotid artery wall thickness measured by multidetector row computed tomography angiography and intimae media thickness measured by sonography |
| url | http://dx.doi.org/10.1100/tsw.2011.147 |
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