Deciphering the alteration of MAP2 interactome caused by a schizophrenia-associated phosphorylation

Deciphering the alteration of MAP2 interactome caused by a schizophrenia-associated phosphorylation

Microtubule-associated protein 2 (MAP2) is a crucial regulator of dendritic structure and neuronal function, orchestrating diverse protein interactions within the microtubule network. We have shown MAP2 is hyperphosphorylated at serine 1782 (S1782) in schizophrenia and phosphomimetic mutation of S17...

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Bibliographic Details
Main Authors: Jiali Lyu, Matthew L MacDonald, Shelby Ruiz, Shinnyi Chou, Jordan Gilardi, Serena C Buchwald, Melanie J Grubisha, Robert A Sweet
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Neurobiology of Disease
Subjects:
MAP2
Proteomics
Protein-protein interaction
Phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996124003334
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