Mesenchymal Tumors of the Liver: An Update Review
Hepatic mesenchymal tumors (HMTs) are non-epithelial benign and malignant tumors with or without specific mesenchymal cell differentiation. They are relatively uncommon. Except for mesenchymal hamartoma, calcified nested stromal–epithelial tumor, and embryonal sarcoma, most mesenchymal lesions are n...
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MDPI AG
2025-02-01
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| author | Joon Hyuk Choi Swan N. Thung |
| author_facet | Joon Hyuk Choi Swan N. Thung |
| author_sort | Joon Hyuk Choi |
| collection | DOAJ |
| description | Hepatic mesenchymal tumors (HMTs) are non-epithelial benign and malignant tumors with or without specific mesenchymal cell differentiation. They are relatively uncommon. Except for mesenchymal hamartoma, calcified nested stromal–epithelial tumor, and embryonal sarcoma, most mesenchymal lesions are not specific to the liver. Pathologists face challenges in diagnosing HMTs due to their diverse morphologies and phenotypic variations. Accurate diagnosis is critical for directing appropriate patient care and predicting outcomes. This review focuses on mesenchymal tumors with a relative predilection for the liver, including vascular and non-vascular mesenchymal neoplasms. It provides a thorough and up-to-date overview, concentrating on clinical and pathological features, differential diagnosis, and diagnostic approaches. |
| format | Article |
| id | doaj-art-73e96354c2fe4cc9a4e4bf604b45965c |
| institution | DOAJ |
| issn | 2227-9059 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj-art-73e96354c2fe4cc9a4e4bf604b45965c2025-08-20T02:44:45ZengMDPI AGBiomedicines2227-90592025-02-0113247910.3390/biomedicines13020479Mesenchymal Tumors of the Liver: An Update ReviewJoon Hyuk Choi0Swan N. Thung1Department of Pathology, Yeungnam University College of Medicine, 170 Hyeonchung-ro, Namgu, Daegu 42415, Republic of KoreaDepartment of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, 1468 Madison Avenue, New York, NY 10029, USAHepatic mesenchymal tumors (HMTs) are non-epithelial benign and malignant tumors with or without specific mesenchymal cell differentiation. They are relatively uncommon. Except for mesenchymal hamartoma, calcified nested stromal–epithelial tumor, and embryonal sarcoma, most mesenchymal lesions are not specific to the liver. Pathologists face challenges in diagnosing HMTs due to their diverse morphologies and phenotypic variations. Accurate diagnosis is critical for directing appropriate patient care and predicting outcomes. This review focuses on mesenchymal tumors with a relative predilection for the liver, including vascular and non-vascular mesenchymal neoplasms. It provides a thorough and up-to-date overview, concentrating on clinical and pathological features, differential diagnosis, and diagnostic approaches.https://www.mdpi.com/2227-9059/13/2/479mesenchymal tumorsliverhemangiomaangiosarcomamesenchymal hamartoma |
| spellingShingle | Joon Hyuk Choi Swan N. Thung Mesenchymal Tumors of the Liver: An Update Review Biomedicines mesenchymal tumors liver hemangioma angiosarcoma mesenchymal hamartoma |
| title | Mesenchymal Tumors of the Liver: An Update Review |
| title_full | Mesenchymal Tumors of the Liver: An Update Review |
| title_fullStr | Mesenchymal Tumors of the Liver: An Update Review |
| title_full_unstemmed | Mesenchymal Tumors of the Liver: An Update Review |
| title_short | Mesenchymal Tumors of the Liver: An Update Review |
| title_sort | mesenchymal tumors of the liver an update review |
| topic | mesenchymal tumors liver hemangioma angiosarcoma mesenchymal hamartoma |
| url | https://www.mdpi.com/2227-9059/13/2/479 |
| work_keys_str_mv | AT joonhyukchoi mesenchymaltumorsoftheliveranupdatereview AT swannthung mesenchymaltumorsoftheliveranupdatereview |