The Impact of Healthcare Pressures on the COVID-19 Hospitalisation Fatality Risk in England
Abstract Background As the impact of the SARS-CoV-2 pandemic extends into 2023 and beyond, the treatment and outcomes of infected patients continues to evolve. Unlike earlier in the pandemic there are now further infectious disease pressures placed on hospitals, which influence patient care and tria...
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| Format: | Article |
| Language: | English |
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Springer
2024-10-01
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| Series: | Journal of Epidemiology and Global Health |
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| Online Access: | https://doi.org/10.1007/s44197-024-00310-9 |
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| author | Jonathon Mellor Owen Jones Thomas Ward |
| author_facet | Jonathon Mellor Owen Jones Thomas Ward |
| author_sort | Jonathon Mellor |
| collection | DOAJ |
| description | Abstract Background As the impact of the SARS-CoV-2 pandemic extends into 2023 and beyond, the treatment and outcomes of infected patients continues to evolve. Unlike earlier in the pandemic there are now further infectious disease pressures placed on hospitals, which influence patient care and triage decisions. Methods The manuscript uses individual patient records linked with associated hospital management information of system pressure characteristics to attribute COVID-19 hospitalisation fatality risks (HFR) to patients and hospitals, using generalised additive mixed effects models. Results Between 01 September 2022 and 09 October 2023, the COVID-19 hospitalisation fatality risk in England was estimated as 12.71% (95% confidence interval (CI) 12.53%, 12.88%). Staff absences had an adjusted odds ratio of 1.038 (95% CI 1.017, 1.060) associated with the HFR when accounting for patient and hospital characteristics. Interpretation This observational research presents evidence that a range of local hospital effects can have a meaningful impact on the risk of death from COVID-19 once hospitalised and should be accounted for when reporting estimates. We show that both the patient case mix and hospital pressures impact estimates of patient outcomes. |
| format | Article |
| id | doaj-art-73e5756d15e14bd4bb1d1f85795f59eb |
| institution | OA Journals |
| issn | 2210-6014 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Springer |
| record_format | Article |
| series | Journal of Epidemiology and Global Health |
| spelling | doaj-art-73e5756d15e14bd4bb1d1f85795f59eb2025-08-20T01:57:11ZengSpringerJournal of Epidemiology and Global Health2210-60142024-10-011441579159010.1007/s44197-024-00310-9The Impact of Healthcare Pressures on the COVID-19 Hospitalisation Fatality Risk in EnglandJonathon Mellor0Owen Jones1Thomas Ward2UK Health Security AgencyUK Health Security AgencyUK Health Security AgencyAbstract Background As the impact of the SARS-CoV-2 pandemic extends into 2023 and beyond, the treatment and outcomes of infected patients continues to evolve. Unlike earlier in the pandemic there are now further infectious disease pressures placed on hospitals, which influence patient care and triage decisions. Methods The manuscript uses individual patient records linked with associated hospital management information of system pressure characteristics to attribute COVID-19 hospitalisation fatality risks (HFR) to patients and hospitals, using generalised additive mixed effects models. Results Between 01 September 2022 and 09 October 2023, the COVID-19 hospitalisation fatality risk in England was estimated as 12.71% (95% confidence interval (CI) 12.53%, 12.88%). Staff absences had an adjusted odds ratio of 1.038 (95% CI 1.017, 1.060) associated with the HFR when accounting for patient and hospital characteristics. Interpretation This observational research presents evidence that a range of local hospital effects can have a meaningful impact on the risk of death from COVID-19 once hospitalised and should be accounted for when reporting estimates. We show that both the patient case mix and hospital pressures impact estimates of patient outcomes.https://doi.org/10.1007/s44197-024-00310-9Hospitalisation fatality riskSARS-CoV-2Hospital strainSeverity estimate |
| spellingShingle | Jonathon Mellor Owen Jones Thomas Ward The Impact of Healthcare Pressures on the COVID-19 Hospitalisation Fatality Risk in England Journal of Epidemiology and Global Health Hospitalisation fatality risk SARS-CoV-2 Hospital strain Severity estimate |
| title | The Impact of Healthcare Pressures on the COVID-19 Hospitalisation Fatality Risk in England |
| title_full | The Impact of Healthcare Pressures on the COVID-19 Hospitalisation Fatality Risk in England |
| title_fullStr | The Impact of Healthcare Pressures on the COVID-19 Hospitalisation Fatality Risk in England |
| title_full_unstemmed | The Impact of Healthcare Pressures on the COVID-19 Hospitalisation Fatality Risk in England |
| title_short | The Impact of Healthcare Pressures on the COVID-19 Hospitalisation Fatality Risk in England |
| title_sort | impact of healthcare pressures on the covid 19 hospitalisation fatality risk in england |
| topic | Hospitalisation fatality risk SARS-CoV-2 Hospital strain Severity estimate |
| url | https://doi.org/10.1007/s44197-024-00310-9 |
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