Pediatric pancreatic perineurioma: A case report
Introduction: Perineuriomas are rare, benign, peripheral nerve sheath tumors that are distinguished from other lesions such as neurofibroma with specific immunohistochemical stains. Case presentation: The patient was an 18-year-old female with a history of spina bifida and neuroblastoma. She was asy...
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Elsevier
2025-03-01
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| Series: | Journal of Pediatric Surgery Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213576625000041 |
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| author | Eakes A Hill B Beierle EA |
| author_facet | Eakes A Hill B Beierle EA |
| author_sort | Eakes A |
| collection | DOAJ |
| description | Introduction: Perineuriomas are rare, benign, peripheral nerve sheath tumors that are distinguished from other lesions such as neurofibroma with specific immunohistochemical stains. Case presentation: The patient was an 18-year-old female with a history of spina bifida and neuroblastoma. She was asymptomatic but at a follow up visit for urinary issues related to her spina bifida, an ultrasound of the kidneys revealed a retroperitoneal mass near the left kidney. Cross sectional imaging was completed and identified a left paraspinous mass measuring 13.3 x 10.1 × 11.2 cm, arising from the pancreas. Laboratory evaluations including liver function tests, complete blood count, renal panel, urine metanephrines, alpha fetoprotein and beta-hCg were normal. Complete resection of the mass required a distal pancreatectomy and splenectomy performed via laparotomy. Histologic evaluation of the mass was consistent with perineurioma. Postoperative recovery was unremarkable and the patient remains free of disease at one year followup with ultrasound imaging. Conclusion: Perineurioma, a rare peripheral nerve sheath neoplasm, should be considered in the differential diagnosis for retroperitoneal masses in the pediatric population. |
| format | Article |
| id | doaj-art-73e537ced49c4f76a38f7eb7ed95a088 |
| institution | DOAJ |
| issn | 2213-5766 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Pediatric Surgery Case Reports |
| spelling | doaj-art-73e537ced49c4f76a38f7eb7ed95a0882025-08-20T03:05:07ZengElsevierJournal of Pediatric Surgery Case Reports2213-57662025-03-0111410295910.1016/j.epsc.2025.102959Pediatric pancreatic perineurioma: A case reportEakes A0Hill B1Beierle EA2Division of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, 35233, USADepartment of Pathology, The Children's Hospital of Alabama, Birmingham, AL, 35233, USADivision of Pediatric Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, 35233, USA; Corresponding author. 1600 7th Ave South, Lowder, Room 300, Birmingham, AL, 35233, USA.Introduction: Perineuriomas are rare, benign, peripheral nerve sheath tumors that are distinguished from other lesions such as neurofibroma with specific immunohistochemical stains. Case presentation: The patient was an 18-year-old female with a history of spina bifida and neuroblastoma. She was asymptomatic but at a follow up visit for urinary issues related to her spina bifida, an ultrasound of the kidneys revealed a retroperitoneal mass near the left kidney. Cross sectional imaging was completed and identified a left paraspinous mass measuring 13.3 x 10.1 × 11.2 cm, arising from the pancreas. Laboratory evaluations including liver function tests, complete blood count, renal panel, urine metanephrines, alpha fetoprotein and beta-hCg were normal. Complete resection of the mass required a distal pancreatectomy and splenectomy performed via laparotomy. Histologic evaluation of the mass was consistent with perineurioma. Postoperative recovery was unremarkable and the patient remains free of disease at one year followup with ultrasound imaging. Conclusion: Perineurioma, a rare peripheral nerve sheath neoplasm, should be considered in the differential diagnosis for retroperitoneal masses in the pediatric population.http://www.sciencedirect.com/science/article/pii/S2213576625000041Pancreatic perineuriomaPediatricNeuroblastomaCase report |
| spellingShingle | Eakes A Hill B Beierle EA Pediatric pancreatic perineurioma: A case report Journal of Pediatric Surgery Case Reports Pancreatic perineurioma Pediatric Neuroblastoma Case report |
| title | Pediatric pancreatic perineurioma: A case report |
| title_full | Pediatric pancreatic perineurioma: A case report |
| title_fullStr | Pediatric pancreatic perineurioma: A case report |
| title_full_unstemmed | Pediatric pancreatic perineurioma: A case report |
| title_short | Pediatric pancreatic perineurioma: A case report |
| title_sort | pediatric pancreatic perineurioma a case report |
| topic | Pancreatic perineurioma Pediatric Neuroblastoma Case report |
| url | http://www.sciencedirect.com/science/article/pii/S2213576625000041 |
| work_keys_str_mv | AT eakesa pediatricpancreaticperineuriomaacasereport AT hillb pediatricpancreaticperineuriomaacasereport AT beierleea pediatricpancreaticperineuriomaacasereport |