Association between sarcopenia on residual back pain after percutaneous kyphoplasty for osteoporotic vertebral compression fractures
Abstract Objective This study aimed to investigate whether sarcopenia affects residual back pain (RBP) after percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCF). Methods We retrospectively analyzed the clinical data of 231 patients with single-segment OVCF treated...
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BMC
2025-05-01
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| Series: | Journal of Orthopaedic Surgery and Research |
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| Online Access: | https://doi.org/10.1186/s13018-025-05902-0 |
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| author | Chengming Li Hangyu Ji Daping Cui Suyang Zhuang Cong Zhang |
| author_facet | Chengming Li Hangyu Ji Daping Cui Suyang Zhuang Cong Zhang |
| author_sort | Chengming Li |
| collection | DOAJ |
| description | Abstract Objective This study aimed to investigate whether sarcopenia affects residual back pain (RBP) after percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCF). Methods We retrospectively analyzed the clinical data of 231 patients with single-segment OVCF treated with PKP between January 2023 and December 2023. Postoperative RBP was assessed at 1 month using the visual analogue scale (VAS). Patients with a VAS score ≥ 4 were classified as the RBP group, while those with a score < 4 served as controls. Sarcopenia was diagnosed using the skeletal muscle mass index (SMI), calculated by dividing the cross-sectional muscle area at the T12 vertebral level (measured via chest CT) by height squared. Univariate analysis compared clinical and imaging data between groups, and binary logistic regression identified risk factors. Result No significant differences were observed between groups in gender, BMI, surgical segment, hypertension, diabetes, or coronary heart disease (P > 0.05). However, age, BMD, SMI, bone cement usage, and sarcopenia prevalence differed significantly (P < 0.05). Binary logistic regression identified BMD and sarcopenia as independent risk factors for RBP after PKP. Conclusion OVCF patients with sarcopenia have a higher likelihood of postoperative RBP, with an incidence approximately twice that of non-sarcopenic patients. Preoperative sarcopenia screening should be prioritized, and postoperative anti-muscular atrophy therapy actively implemented. |
| format | Article |
| id | doaj-art-73de983fc8324fed989292ef984813c0 |
| institution | OA Journals |
| issn | 1749-799X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj-art-73de983fc8324fed989292ef984813c02025-08-20T01:59:57ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2025-05-012011710.1186/s13018-025-05902-0Association between sarcopenia on residual back pain after percutaneous kyphoplasty for osteoporotic vertebral compression fracturesChengming Li0Hangyu Ji1Daping Cui2Suyang Zhuang3Cong Zhang4Department of Spinal Surgery Center, Zhongda Hospital Southeast UniversityDepartment of Spinal Surgery Center, Zhongda Hospital Southeast UniversityDepartment of Orthopedics, Shenzhen Bao’an District Central HospitalDepartment of Spinal Surgery Center, Zhongda Hospital Southeast UniversityDepartment of Spinal Surgery Center, Zhongda Hospital Southeast UniversityAbstract Objective This study aimed to investigate whether sarcopenia affects residual back pain (RBP) after percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCF). Methods We retrospectively analyzed the clinical data of 231 patients with single-segment OVCF treated with PKP between January 2023 and December 2023. Postoperative RBP was assessed at 1 month using the visual analogue scale (VAS). Patients with a VAS score ≥ 4 were classified as the RBP group, while those with a score < 4 served as controls. Sarcopenia was diagnosed using the skeletal muscle mass index (SMI), calculated by dividing the cross-sectional muscle area at the T12 vertebral level (measured via chest CT) by height squared. Univariate analysis compared clinical and imaging data between groups, and binary logistic regression identified risk factors. Result No significant differences were observed between groups in gender, BMI, surgical segment, hypertension, diabetes, or coronary heart disease (P > 0.05). However, age, BMD, SMI, bone cement usage, and sarcopenia prevalence differed significantly (P < 0.05). Binary logistic regression identified BMD and sarcopenia as independent risk factors for RBP after PKP. Conclusion OVCF patients with sarcopenia have a higher likelihood of postoperative RBP, with an incidence approximately twice that of non-sarcopenic patients. Preoperative sarcopenia screening should be prioritized, and postoperative anti-muscular atrophy therapy actively implemented.https://doi.org/10.1186/s13018-025-05902-0SarcopeniaOsteoporotic vertebral compression fracturePercutaneous kyphoplastyResidual back pain |
| spellingShingle | Chengming Li Hangyu Ji Daping Cui Suyang Zhuang Cong Zhang Association between sarcopenia on residual back pain after percutaneous kyphoplasty for osteoporotic vertebral compression fractures Journal of Orthopaedic Surgery and Research Sarcopenia Osteoporotic vertebral compression fracture Percutaneous kyphoplasty Residual back pain |
| title | Association between sarcopenia on residual back pain after percutaneous kyphoplasty for osteoporotic vertebral compression fractures |
| title_full | Association between sarcopenia on residual back pain after percutaneous kyphoplasty for osteoporotic vertebral compression fractures |
| title_fullStr | Association between sarcopenia on residual back pain after percutaneous kyphoplasty for osteoporotic vertebral compression fractures |
| title_full_unstemmed | Association between sarcopenia on residual back pain after percutaneous kyphoplasty for osteoporotic vertebral compression fractures |
| title_short | Association between sarcopenia on residual back pain after percutaneous kyphoplasty for osteoporotic vertebral compression fractures |
| title_sort | association between sarcopenia on residual back pain after percutaneous kyphoplasty for osteoporotic vertebral compression fractures |
| topic | Sarcopenia Osteoporotic vertebral compression fracture Percutaneous kyphoplasty Residual back pain |
| url | https://doi.org/10.1186/s13018-025-05902-0 |
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