MuSK is a substrate for CaMK2β but this interaction is dispensable for MuSK activation in vivo
Abstract The neuromuscular junction (NMJ) is the unique interface between lower motor neurons and skeletal muscle fibers and is indispensable for muscle function. Tight control of its localized formation at the center of every muscle fiber, and maintenance throughout lifetime are sustained by muscle...
Saved in:
| Main Authors: | Jakob J. Prömer, Sara Wolske, Perrine Castets, Geeske M. van Woerden, Cinzia Barresi, Kevin C. O’Connor, Ruth Herbst |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-95053-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
MuSK-Myasthenia Gravis Unmasked by Hydroxychloroquine
by: Shalini Bhaskar, et al.
Published: (2022-01-01) -
Patient-specific therapeutic benefit of MuSK agonist antibody ARGX-119 in MuSK myasthenia gravis passive transfer models
by: Jamie L. Lim, et al.
Published: (2025-02-01) -
A mutation causes MuSK reduced sensitivity to agrin and congenital myasthenia.
by: Asma Ben Ammar, et al.
Published: (2013-01-01) -
Myasthenia Crisis as First Presentation of MuSk Positive Myasthenia Gravis: A Case Report
by: Dipesh Chhetri, et al.
Published: (2025-02-01) -
MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters.
by: Inga Koneczny, et al.
Published: (2013-01-01)