Bone organoid 3D bioprinting: Construction and application in bone regeneration

Repair of critical-size bone defects remains a significant challenge. In recent years, organoid technology has emerged as a promising strategy for bone regeneration, but developing bone organoids with complex structure and function still faces many hurdles. Three-dimensional (3D) bioprinting, a revo...

Full description

Saved in:
Bibliographic Details
Main Authors: Tang Zihui, Zhong Chang, Luo Jiayu, Wang Qi, Zhou Ping
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:BIO Web of Conferences
Online Access:https://www.bio-conferences.org/articles/bioconf/pdf/2025/25/bioconf_icbb2025_02005.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849730516070170624
author Tang Zihui
Zhong Chang
Luo Jiayu
Wang Qi
Zhou Ping
author_facet Tang Zihui
Zhong Chang
Luo Jiayu
Wang Qi
Zhou Ping
author_sort Tang Zihui
collection DOAJ
description Repair of critical-size bone defects remains a significant challenge. In recent years, organoid technology has emerged as a promising strategy for bone regeneration, but developing bone organoids with complex structure and function still faces many hurdles. Three-dimensional (3D) bioprinting, a revolutionary additive manufacturing technology, can precisely deposit bioink layer by layer with a specific pattern to construct the required 3D structure, which provides a simpler and more efficient method for generating bone organoids. This review summarizes the 3D bioprinting strategies of bone organoids and their application in bone regeneration in order to provide a reference for future research.
format Article
id doaj-art-73d66e2da0ec493b8d14e1e9f4ff9c1e
institution DOAJ
issn 2117-4458
language English
publishDate 2025-01-01
publisher EDP Sciences
record_format Article
series BIO Web of Conferences
spelling doaj-art-73d66e2da0ec493b8d14e1e9f4ff9c1e2025-08-20T03:08:51ZengEDP SciencesBIO Web of Conferences2117-44582025-01-011740200510.1051/bioconf/202517402005bioconf_icbb2025_02005Bone organoid 3D bioprinting: Construction and application in bone regenerationTang Zihui0Zhong Chang1Luo Jiayu2Wang Qi3Zhou Ping4School of Stomatology, Lanzhou UniversitySchool of Stomatology, Lanzhou UniversitySchool of Stomatology, Lanzhou UniversitySchool of Stomatology, Lanzhou UniversitySchool of Stomatology, Lanzhou UniversityRepair of critical-size bone defects remains a significant challenge. In recent years, organoid technology has emerged as a promising strategy for bone regeneration, but developing bone organoids with complex structure and function still faces many hurdles. Three-dimensional (3D) bioprinting, a revolutionary additive manufacturing technology, can precisely deposit bioink layer by layer with a specific pattern to construct the required 3D structure, which provides a simpler and more efficient method for generating bone organoids. This review summarizes the 3D bioprinting strategies of bone organoids and their application in bone regeneration in order to provide a reference for future research.https://www.bio-conferences.org/articles/bioconf/pdf/2025/25/bioconf_icbb2025_02005.pdf
spellingShingle Tang Zihui
Zhong Chang
Luo Jiayu
Wang Qi
Zhou Ping
Bone organoid 3D bioprinting: Construction and application in bone regeneration
BIO Web of Conferences
title Bone organoid 3D bioprinting: Construction and application in bone regeneration
title_full Bone organoid 3D bioprinting: Construction and application in bone regeneration
title_fullStr Bone organoid 3D bioprinting: Construction and application in bone regeneration
title_full_unstemmed Bone organoid 3D bioprinting: Construction and application in bone regeneration
title_short Bone organoid 3D bioprinting: Construction and application in bone regeneration
title_sort bone organoid 3d bioprinting construction and application in bone regeneration
url https://www.bio-conferences.org/articles/bioconf/pdf/2025/25/bioconf_icbb2025_02005.pdf
work_keys_str_mv AT tangzihui boneorganoid3dbioprintingconstructionandapplicationinboneregeneration
AT zhongchang boneorganoid3dbioprintingconstructionandapplicationinboneregeneration
AT luojiayu boneorganoid3dbioprintingconstructionandapplicationinboneregeneration
AT wangqi boneorganoid3dbioprintingconstructionandapplicationinboneregeneration
AT zhouping boneorganoid3dbioprintingconstructionandapplicationinboneregeneration