Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experience
Purpose: Prostate biopsy remains the key step in prostate cancer detection. In recent years, the PrecisionPoint™ Transperineal Access System (PPTAS) has been described as an effective and safe method for performing transperineal biopsy under local anaesthesia (LA). The authors report on the real-wor...
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| Format: | Article |
| Language: | English |
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Korean Urological Association
2025-07-01
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| Series: | Investigative and Clinical Urology |
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| Online Access: | https://www.icurology.org/pdf/10.4111/icu.20250077 |
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| author | Ahmed Tarek Albnhawy Ayman Mostafa Eslam Hussain George Hanna Shweta Das Asmita Hossain Moumn Abdalla Jordan Durrant Panagiotis Papikinos |
| author_facet | Ahmed Tarek Albnhawy Ayman Mostafa Eslam Hussain George Hanna Shweta Das Asmita Hossain Moumn Abdalla Jordan Durrant Panagiotis Papikinos |
| author_sort | Ahmed Tarek Albnhawy |
| collection | DOAJ |
| description | Purpose: Prostate biopsy remains the key step in prostate cancer detection. In recent years, the PrecisionPoint™ Transperineal Access System (PPTAS) has been described as an effective and safe method for performing transperineal biopsy under local anaesthesia (LA). The authors report on the real-world experience of the procedure.
Materials and Methods: Following introduction and familiarity with the PPTAS biopsy method, patients undergoing prostate biopsy for suspected prostate cancer were provided with validated questionnaires to rate their pain and discomfort following the procedure. The experience of LA administration and the experience of the biopsies were rated separately and prospectively. In addition, the number of cores, maximum core length (MCL), detection rate, and complication rate were retrospectively collected.
Results: One hundred three patients were recruited to the study, and a final number of 86 completed patient-reported outcome measures (PROMs) forms were analysed. The procedure was described as tolerable by 97.7%, causing discomfort in 70.9%–88.4%. The grade of pain or discomfort in 73.3%–87.2% was <4 on the pain scale, with only 5.8%–9.3% describing a pain grade >5 on the pain scale. The number of cores, MCL, detection rate, and complication rate were within accepted rates.
Conclusions: In a real-world setting, the procedure showed satisfactory PROMs with good patient tolerability and a low grade of pain. Also, it showed a good biopsy quality, detection rate, and complications rate, meaning PPTAS should be considered by centers seeking to streamline the prostate cancer detection pathway for patients. |
| format | Article |
| id | doaj-art-73d2998301da450cb35f4cf93e2dbd66 |
| institution | Kabale University |
| issn | 2466-0493 2466-054X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Korean Urological Association |
| record_format | Article |
| series | Investigative and Clinical Urology |
| spelling | doaj-art-73d2998301da450cb35f4cf93e2dbd662025-08-20T03:50:05ZengKorean Urological AssociationInvestigative and Clinical Urology2466-04932466-054X2025-07-0166431131910.4111/icu.20250077Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experienceAhmed Tarek Albnhawy0https://orcid.org/0009-0005-3879-8884Ayman Mostafa1https://orcid.org/0009-0000-2231-3698Eslam Hussain2https://orcid.org/0009-0008-7559-0726George Hanna3https://orcid.org/0000-0001-5704-5195Shweta Das4https://orcid.org/0009-0007-8944-2380Asmita Hossain5https://orcid.org/0009-0008-7399-2115Moumn Abdalla6https://orcid.org/0009-0007-3004-3756Jordan Durrant7https://orcid.org/0009-0002-0967-5330Panagiotis Papikinos8https://orcid.org/0009-0005-3233-8596Department of Urology, Surrey and Sussex Healthcare NHS Trust, Redhill, UK.Department of Urology, Surrey and Sussex Healthcare NHS Trust, Redhill, UK.Department of Urology, Surrey and Sussex Healthcare NHS Trust, Redhill, UK.Department of Urology, Surrey and Sussex Healthcare NHS Trust, Redhill, UK.Department of Urology, Surrey and Sussex Healthcare NHS Trust, Redhill, UK.Department of Urology, Surrey and Sussex Healthcare NHS Trust, Redhill, UK.Department of Urology, Surrey and Sussex Healthcare NHS Trust, Redhill, UK.Department of Urology, Surrey and Sussex Healthcare NHS Trust, Redhill, UK.Department of Urology, Surrey and Sussex Healthcare NHS Trust, Redhill, UK.Purpose: Prostate biopsy remains the key step in prostate cancer detection. In recent years, the PrecisionPoint™ Transperineal Access System (PPTAS) has been described as an effective and safe method for performing transperineal biopsy under local anaesthesia (LA). The authors report on the real-world experience of the procedure. Materials and Methods: Following introduction and familiarity with the PPTAS biopsy method, patients undergoing prostate biopsy for suspected prostate cancer were provided with validated questionnaires to rate their pain and discomfort following the procedure. The experience of LA administration and the experience of the biopsies were rated separately and prospectively. In addition, the number of cores, maximum core length (MCL), detection rate, and complication rate were retrospectively collected. Results: One hundred three patients were recruited to the study, and a final number of 86 completed patient-reported outcome measures (PROMs) forms were analysed. The procedure was described as tolerable by 97.7%, causing discomfort in 70.9%–88.4%. The grade of pain or discomfort in 73.3%–87.2% was <4 on the pain scale, with only 5.8%–9.3% describing a pain grade >5 on the pain scale. The number of cores, MCL, detection rate, and complication rate were within accepted rates. Conclusions: In a real-world setting, the procedure showed satisfactory PROMs with good patient tolerability and a low grade of pain. Also, it showed a good biopsy quality, detection rate, and complications rate, meaning PPTAS should be considered by centers seeking to streamline the prostate cancer detection pathway for patients.https://www.icurology.org/pdf/10.4111/icu.20250077anesthesialocalbiopsypainpatient reported outcome measuresprostatic neoplasms |
| spellingShingle | Ahmed Tarek Albnhawy Ayman Mostafa Eslam Hussain George Hanna Shweta Das Asmita Hossain Moumn Abdalla Jordan Durrant Panagiotis Papikinos Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experience Investigative and Clinical Urology anesthesia local biopsy pain patient reported outcome measures prostatic neoplasms |
| title | Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experience |
| title_full | Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experience |
| title_fullStr | Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experience |
| title_full_unstemmed | Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experience |
| title_short | Patient-reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the PrecisionPoint™ transperineal access system: A prospective study for a real-world patient experience |
| title_sort | patient reported outcome measures for pain and tolerability of transperineal prostate biopsy under local anaesthesia using the precisionpoint™ transperineal access system a prospective study for a real world patient experience |
| topic | anesthesia local biopsy pain patient reported outcome measures prostatic neoplasms |
| url | https://www.icurology.org/pdf/10.4111/icu.20250077 |
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