Piperacillin-Associated Pulmonary Infiltrates with Eosinophilia: A Case Report
A case of pulmonary infiltrates with eosinophilia attributed to piperacillin/tazobactam therapy is described. A 54-year-old woman was treated for a suspected severe urinary tract infection with piperacillin/tazobactam. Four days later, she developed fever, chills, shortness of breath and intermitten...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2010/670153 |
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| author | Olivia Ling-I Tseng John Thomas Kelsall Pearce George Wilcox |
| author_facet | Olivia Ling-I Tseng John Thomas Kelsall Pearce George Wilcox |
| author_sort | Olivia Ling-I Tseng |
| collection | DOAJ |
| description | A case of pulmonary infiltrates with eosinophilia attributed to piperacillin/tazobactam therapy is described. A 54-year-old woman was treated for a suspected severe urinary tract infection with piperacillin/tazobactam. Four days later, she developed fever, chills, shortness of breath and intermittent chest pains. Eosinophilia was noted in peripheral blood and, subsequently, on bronchoalveolar lavage. Transbronchial biopsy showed tissue infiltrates with eosinophilia. No evidence of bacterial, fungal and parasitic infection, or vasculitis was observed. Her symptoms and peripheral eosinophilia subsided after drug discontinuation and oral prednisone treatment. Piperacillin is an extended-spectrum penicillin antibiotic prescribed for moderate to severe infections. The common adverse reactions to piperacillin include nausea, vomiting, diarrhea and rash. Pulmonary infiltrates with eosinophilia is a rare adverse reaction, but one that may result in significant morbidity. Physicians should be aware of this rare but important adverse reaction to piperacillin. |
| format | Article |
| id | doaj-art-73d0d98243b646ddadd1c4a38e3bcd31 |
| institution | Kabale University |
| issn | 1198-2241 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-73d0d98243b646ddadd1c4a38e3bcd312025-02-03T01:31:17ZengWileyCanadian Respiratory Journal1198-22412010-01-01172e24e2610.1155/2010/670153Piperacillin-Associated Pulmonary Infiltrates with Eosinophilia: A Case ReportOlivia Ling-I Tseng0John Thomas Kelsall1Pearce George Wilcox2Department of Internal Medicine, St Paul’s Hospital, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Internal Medicine, St Paul’s Hospital, University of British Columbia, Vancouver, British Columbia, CanadaDepartment of Internal Medicine, St Paul’s Hospital, University of British Columbia, Vancouver, British Columbia, CanadaA case of pulmonary infiltrates with eosinophilia attributed to piperacillin/tazobactam therapy is described. A 54-year-old woman was treated for a suspected severe urinary tract infection with piperacillin/tazobactam. Four days later, she developed fever, chills, shortness of breath and intermittent chest pains. Eosinophilia was noted in peripheral blood and, subsequently, on bronchoalveolar lavage. Transbronchial biopsy showed tissue infiltrates with eosinophilia. No evidence of bacterial, fungal and parasitic infection, or vasculitis was observed. Her symptoms and peripheral eosinophilia subsided after drug discontinuation and oral prednisone treatment. Piperacillin is an extended-spectrum penicillin antibiotic prescribed for moderate to severe infections. The common adverse reactions to piperacillin include nausea, vomiting, diarrhea and rash. Pulmonary infiltrates with eosinophilia is a rare adverse reaction, but one that may result in significant morbidity. Physicians should be aware of this rare but important adverse reaction to piperacillin.http://dx.doi.org/10.1155/2010/670153 |
| spellingShingle | Olivia Ling-I Tseng John Thomas Kelsall Pearce George Wilcox Piperacillin-Associated Pulmonary Infiltrates with Eosinophilia: A Case Report Canadian Respiratory Journal |
| title | Piperacillin-Associated Pulmonary Infiltrates with Eosinophilia: A Case Report |
| title_full | Piperacillin-Associated Pulmonary Infiltrates with Eosinophilia: A Case Report |
| title_fullStr | Piperacillin-Associated Pulmonary Infiltrates with Eosinophilia: A Case Report |
| title_full_unstemmed | Piperacillin-Associated Pulmonary Infiltrates with Eosinophilia: A Case Report |
| title_short | Piperacillin-Associated Pulmonary Infiltrates with Eosinophilia: A Case Report |
| title_sort | piperacillin associated pulmonary infiltrates with eosinophilia a case report |
| url | http://dx.doi.org/10.1155/2010/670153 |
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