Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties
Trichosanthes dioica Roxb. is a climber of the Cucurbitaceae family mainly found in tropical Asia. The fruit is widely consumed as a vegetable and different parts of this plant are used in the traditional medicine to treat various types of human ailments. In this review, we critically analyzed and p...
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| Language: | English |
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Tsinghua University Press
2018-03-01
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| Series: | Food Science and Human Wellness |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453017301295 |
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| author | Mahia Khandaker Saleha Akter Mohammad Zafar Imam |
| author_facet | Mahia Khandaker Saleha Akter Mohammad Zafar Imam |
| author_sort | Mahia Khandaker |
| collection | DOAJ |
| description | Trichosanthes dioica Roxb. is a climber of the Cucurbitaceae family mainly found in tropical Asia. The fruit is widely consumed as a vegetable and different parts of this plant are used in the traditional medicine to treat various types of human ailments. In this review, we critically analyzed and presented the scientific studies on T. dioica available in three electronic databases viz. PubMed, Web of Science and Google Scholar. Our aim was to find the scientific basis of the traditional use to understand the plant’s potential in therapy. Studies have found promising antihyperglycemic, antihyperlipidemic, antitumor, cytotoxic, arsenic poisoning ameliorative, anti-inflammatory, antidiarrheal, and varieties of pharmacological activities of T. dioica. Different types of bioactive compounds have been identified and isolated from T. dioica including peptides namely trichosanthin and lectin; a number of triterpenes like cucurbitacin B, euphol, α-amyrin, β-amyrin, lupeol, taraxerol, betulin, and karounidiol; sterols, steroidal saponin, tannin, flavonoids etc. T. dioica contains a number of well-known bioactive phytochemicals and the plant has shown an array of pharmacological activities in vivo. This review will expand our understanding of the therapeutic potential of T. dioica and their phytochemical basis which may help in further research on this species. Keywords: Trichosanthes dioica, Pointed gourd, Cucurbitaceae, Ethnomedicine, Ethnopharmacology |
| format | Article |
| id | doaj-art-73c9789716b64051861a8d6fbe13c9bb |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2018-03-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-73c9789716b64051861a8d6fbe13c9bb2025-02-03T06:34:59ZengTsinghua University PressFood Science and Human Wellness2213-45302018-03-01713448Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological propertiesMahia Khandaker0Saleha Akter1Mohammad Zafar Imam2Department of Biotechnology, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Salna, Gazipur 1706, BangladeshDepartment of Pharmacy, Primeasia University, HBR Tower, 9 Banani, Dhaka 1213, BangladeshDepartment of Pharmacy, Stamford University Bangladesh, 51 Siddeswari Road, Dhaka 1217, Bangladesh; Corresponding author at: Department of Pharmacy, Stamford University Bangladesh, 51 Siddeswari Road, Dhaka 1217, Bangladesh.Trichosanthes dioica Roxb. is a climber of the Cucurbitaceae family mainly found in tropical Asia. The fruit is widely consumed as a vegetable and different parts of this plant are used in the traditional medicine to treat various types of human ailments. In this review, we critically analyzed and presented the scientific studies on T. dioica available in three electronic databases viz. PubMed, Web of Science and Google Scholar. Our aim was to find the scientific basis of the traditional use to understand the plant’s potential in therapy. Studies have found promising antihyperglycemic, antihyperlipidemic, antitumor, cytotoxic, arsenic poisoning ameliorative, anti-inflammatory, antidiarrheal, and varieties of pharmacological activities of T. dioica. Different types of bioactive compounds have been identified and isolated from T. dioica including peptides namely trichosanthin and lectin; a number of triterpenes like cucurbitacin B, euphol, α-amyrin, β-amyrin, lupeol, taraxerol, betulin, and karounidiol; sterols, steroidal saponin, tannin, flavonoids etc. T. dioica contains a number of well-known bioactive phytochemicals and the plant has shown an array of pharmacological activities in vivo. This review will expand our understanding of the therapeutic potential of T. dioica and their phytochemical basis which may help in further research on this species. Keywords: Trichosanthes dioica, Pointed gourd, Cucurbitaceae, Ethnomedicine, Ethnopharmacologyhttp://www.sciencedirect.com/science/article/pii/S2213453017301295 |
| spellingShingle | Mahia Khandaker Saleha Akter Mohammad Zafar Imam Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties Food Science and Human Wellness |
| title | Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties |
| title_full | Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties |
| title_fullStr | Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties |
| title_full_unstemmed | Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties |
| title_short | Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties |
| title_sort | trichosanthes dioica roxb a vegetable with diverse pharmacological properties |
| url | http://www.sciencedirect.com/science/article/pii/S2213453017301295 |
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