Theoretical investigation of solvent effects on reactivity, spectroscopic properties, and inhibitory potential of a dihydropyridine derivative against Vibrio cholorae: DFT, molecular docking and pharmacokinetics evaluation

Abstract The emergence of drug-resistant bacterial strains has made cholera an imminent threat to health. Addressing this challenge requires an exploration of new alternative medicines. In this work, density functional theory at B3LYP/6-311G (d, p) was employed to examine the effect of solvents on 4...

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Bibliographic Details
Main Authors: Israel A. Ekoro, Justina I. Mbonu, Christiana E. Ogwuche, Sabina C. Agu, Hamzah A. Bawa
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Chemistry
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Online Access:https://doi.org/10.1007/s44371-025-00189-w
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