Assessment of the feed additive consisting of Saccharomyces cerevisiae NCYC R404 for dairy cows for the renewal of its authorisation (Volac International Ltd)

Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of the authorisation of Saccharomyces cerevisiae NCYC R404 as a zootechnical additive (functional group: gut flora stabilisers) for dairy cows. T...

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Main Authors: EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Ilen Röhe, Katerina Theodoridou, Andrey Yurkov, Montserrat Anguita, Nicole Bozzi Cionci, Rosella Brozzi, Yolanda García‐Cazorla, Jordi Tarrés‐Call, Piera Valeri, Matteo L. Innocenti
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:EFSA Journal
Subjects:
Online Access:https://doi.org/10.2903/j.efsa.2025.9342
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author EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Roberto Edoardo Villa
Giovanna Azimonti
Eleftherios Bonos
Henrik Christensen
Mojca Durjava
Birgit Dusemund
Ronette Gehring
Boet Glandorf
Maryline Kouba
Marta López‐Alonso
Francesca Marcon
Carlo Nebbia
Alena Pechová
Miguel Prieto‐Maradona
Ilen Röhe
Katerina Theodoridou
Andrey Yurkov
Montserrat Anguita
Nicole Bozzi Cionci
Rosella Brozzi
Yolanda García‐Cazorla
Jordi Tarrés‐Call
Piera Valeri
Matteo L. Innocenti
author_facet EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Roberto Edoardo Villa
Giovanna Azimonti
Eleftherios Bonos
Henrik Christensen
Mojca Durjava
Birgit Dusemund
Ronette Gehring
Boet Glandorf
Maryline Kouba
Marta López‐Alonso
Francesca Marcon
Carlo Nebbia
Alena Pechová
Miguel Prieto‐Maradona
Ilen Röhe
Katerina Theodoridou
Andrey Yurkov
Montserrat Anguita
Nicole Bozzi Cionci
Rosella Brozzi
Yolanda García‐Cazorla
Jordi Tarrés‐Call
Piera Valeri
Matteo L. Innocenti
author_sort EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
collection DOAJ
description Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of the authorisation of Saccharomyces cerevisiae NCYC R404 as a zootechnical additive (functional group: gut flora stabilisers) for dairy cows. The applicant has provided evidence that the additive currently on the market complies with the existing conditions of authorisation. There was no new evidence that would lead the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) to reconsider its previous conclusions on the safety of the product for the target species, consumers and the environment, for which the additive is considered to remain safe. Regarding user safety, the Panel reiterates its previous conclusions that the additive is not irritant to eyes and skin but should be considered a potential skin and respiratory sensitiser, and any exposure through skin and respiratory tract is considered a risk. There is no need for assessing the efficacy of the additive in the context of renewal of the authorisation.
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spelling doaj-art-73c808f0d6b4476cbfce89a1af19be0d2025-08-20T03:33:17ZengWileyEFSA Journal1831-47322025-04-01234n/an/a10.2903/j.efsa.2025.9342Assessment of the feed additive consisting of Saccharomyces cerevisiae NCYC R404 for dairy cows for the renewal of its authorisation (Volac International Ltd)EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)Roberto Edoardo VillaGiovanna AzimontiEleftherios BonosHenrik ChristensenMojca DurjavaBirgit DusemundRonette GehringBoet GlandorfMaryline KoubaMarta López‐AlonsoFrancesca MarconCarlo NebbiaAlena PechováMiguel Prieto‐MaradonaIlen RöheKaterina TheodoridouAndrey YurkovMontserrat AnguitaNicole Bozzi CionciRosella BrozziYolanda García‐CazorlaJordi Tarrés‐CallPiera ValeriMatteo L. InnocentiAbstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of the authorisation of Saccharomyces cerevisiae NCYC R404 as a zootechnical additive (functional group: gut flora stabilisers) for dairy cows. The applicant has provided evidence that the additive currently on the market complies with the existing conditions of authorisation. There was no new evidence that would lead the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) to reconsider its previous conclusions on the safety of the product for the target species, consumers and the environment, for which the additive is considered to remain safe. Regarding user safety, the Panel reiterates its previous conclusions that the additive is not irritant to eyes and skin but should be considered a potential skin and respiratory sensitiser, and any exposure through skin and respiratory tract is considered a risk. There is no need for assessing the efficacy of the additive in the context of renewal of the authorisation.https://doi.org/10.2903/j.efsa.2025.9342gut flora stabilisersSaccharomyces cerevisiae NCYC R404safetyzootechnical additives
spellingShingle EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
Roberto Edoardo Villa
Giovanna Azimonti
Eleftherios Bonos
Henrik Christensen
Mojca Durjava
Birgit Dusemund
Ronette Gehring
Boet Glandorf
Maryline Kouba
Marta López‐Alonso
Francesca Marcon
Carlo Nebbia
Alena Pechová
Miguel Prieto‐Maradona
Ilen Röhe
Katerina Theodoridou
Andrey Yurkov
Montserrat Anguita
Nicole Bozzi Cionci
Rosella Brozzi
Yolanda García‐Cazorla
Jordi Tarrés‐Call
Piera Valeri
Matteo L. Innocenti
Assessment of the feed additive consisting of Saccharomyces cerevisiae NCYC R404 for dairy cows for the renewal of its authorisation (Volac International Ltd)
EFSA Journal
gut flora stabilisers
Saccharomyces cerevisiae NCYC R404
safety
zootechnical additives
title Assessment of the feed additive consisting of Saccharomyces cerevisiae NCYC R404 for dairy cows for the renewal of its authorisation (Volac International Ltd)
title_full Assessment of the feed additive consisting of Saccharomyces cerevisiae NCYC R404 for dairy cows for the renewal of its authorisation (Volac International Ltd)
title_fullStr Assessment of the feed additive consisting of Saccharomyces cerevisiae NCYC R404 for dairy cows for the renewal of its authorisation (Volac International Ltd)
title_full_unstemmed Assessment of the feed additive consisting of Saccharomyces cerevisiae NCYC R404 for dairy cows for the renewal of its authorisation (Volac International Ltd)
title_short Assessment of the feed additive consisting of Saccharomyces cerevisiae NCYC R404 for dairy cows for the renewal of its authorisation (Volac International Ltd)
title_sort assessment of the feed additive consisting of saccharomyces cerevisiae ncyc r404 for dairy cows for the renewal of its authorisation volac international ltd
topic gut flora stabilisers
Saccharomyces cerevisiae NCYC R404
safety
zootechnical additives
url https://doi.org/10.2903/j.efsa.2025.9342
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