Seasonal dynamics and risk assessment of antibiotic resistome in straw-retained agroecosystems

Straw retention (SR) is an essential management practice of sustainable agriculture. However, the seasonal dynamics on the antibiotic resistome and associated ecological risks in seasonally frozen agroecosystems remain unclear. Here, we conducted a multi-site field study in the Sanjiang Plain, a sea...

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Main Authors: Yi Wu, Yi Fan, Yiheng Tao, Quankuan Guo, Shuang Pang, Wei Yang, Ximei Zhang
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325009753
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author Yi Wu
Yi Fan
Yiheng Tao
Quankuan Guo
Shuang Pang
Wei Yang
Ximei Zhang
author_facet Yi Wu
Yi Fan
Yiheng Tao
Quankuan Guo
Shuang Pang
Wei Yang
Ximei Zhang
author_sort Yi Wu
collection DOAJ
description Straw retention (SR) is an essential management practice of sustainable agriculture. However, the seasonal dynamics on the antibiotic resistome and associated ecological risks in seasonally frozen agroecosystems remain unclear. Here, we conducted a multi-site field study in the Sanjiang Plain, a seasonally frozen agricultural region of Northeast China, combining time-series soil sampling with metagenomic sequencing to reveal antibiotic resistome dynamics. SR elevated relative abundance of antibiotic resistance genes (ARGs) across all seasons and induced significant seasonal variations in richness. ARG richness peaked during freezing season favoring the dominance of low-risk ARGs. The soil C/N ratio emerged as the primary driver shaping the relative abundance and diversity of antibiotic resistome, with 23 core low-risk ARGs accounting for 73 % of the observed abundance increase, whereas high-risk ARGs constituted merely 0.44 % of the total resistome abundance. Straw retention also reduced interactions among high-risk ARGs with ecological risk remaining stable, demonstrating decoupling between resistome abundance and environmental risk. Structural equation modeling revealed straw retention exerting both direct effects (0.45) and indirect regulation (-0.16) via modulating nutrient content. Our findings evaluated the antibiotic resistance risks of straw retention with the enrichment of low-risk ARGs and suppression of interactions among high-risk ARGs, promoting its safe adoption in agroecosystems. Overall, this study provides a comprehensive antibiotic risk assessment framework, demonstrating straw retention as a beneficial strategy that enhances soil fertility with practically manageable resistance risks in agroecosystems.
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spelling doaj-art-73c254b88b78415982b4c2abd4f826d12025-08-20T03:03:58ZengElsevierEcotoxicology and Environmental Safety0147-65132025-09-0130211863010.1016/j.ecoenv.2025.118630Seasonal dynamics and risk assessment of antibiotic resistome in straw-retained agroecosystemsYi Wu0Yi Fan1Yiheng Tao2Quankuan Guo3Shuang Pang4Wei Yang5Ximei Zhang6Key Laboratory of Dryland Agriculture, Ministry of Agriculture, Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China; State Key Laboratory of Efficient Utilization of Agricultural Water Resources, CAU/CAAS, ChinaKey Laboratory of Dryland Agriculture, Ministry of Agriculture, Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China; State Key Laboratory of Efficient Utilization of Agricultural Water Resources, CAU/CAAS, ChinaKey Laboratory of Dryland Agriculture, Ministry of Agriculture, Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China; State Key Laboratory of Efficient Utilization of Agricultural Water Resources, CAU/CAAS, China; College of Land and Environment, Shenyang Agricultural University, Shenyang 110161, ChinaKey Laboratory of Dryland Agriculture, Ministry of Agriculture, Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China; State Key Laboratory of Efficient Utilization of Agricultural Water Resources, CAU/CAAS, ChinaKey Laboratory of Dryland Agriculture, Ministry of Agriculture, Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China; State Key Laboratory of Efficient Utilization of Agricultural Water Resources, CAU/CAAS, ChinaKey Laboratory of Dryland Agriculture, Ministry of Agriculture, Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China; State Key Laboratory of Efficient Utilization of Agricultural Water Resources, CAU/CAAS, China; Corresponding authors at: Key Laboratory of Dryland Agriculture, Ministry of Agriculture, Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China.Key Laboratory of Dryland Agriculture, Ministry of Agriculture, Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China; State Key Laboratory of Efficient Utilization of Agricultural Water Resources, CAU/CAAS, China; Corresponding authors at: Key Laboratory of Dryland Agriculture, Ministry of Agriculture, Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China.Straw retention (SR) is an essential management practice of sustainable agriculture. However, the seasonal dynamics on the antibiotic resistome and associated ecological risks in seasonally frozen agroecosystems remain unclear. Here, we conducted a multi-site field study in the Sanjiang Plain, a seasonally frozen agricultural region of Northeast China, combining time-series soil sampling with metagenomic sequencing to reveal antibiotic resistome dynamics. SR elevated relative abundance of antibiotic resistance genes (ARGs) across all seasons and induced significant seasonal variations in richness. ARG richness peaked during freezing season favoring the dominance of low-risk ARGs. The soil C/N ratio emerged as the primary driver shaping the relative abundance and diversity of antibiotic resistome, with 23 core low-risk ARGs accounting for 73 % of the observed abundance increase, whereas high-risk ARGs constituted merely 0.44 % of the total resistome abundance. Straw retention also reduced interactions among high-risk ARGs with ecological risk remaining stable, demonstrating decoupling between resistome abundance and environmental risk. Structural equation modeling revealed straw retention exerting both direct effects (0.45) and indirect regulation (-0.16) via modulating nutrient content. Our findings evaluated the antibiotic resistance risks of straw retention with the enrichment of low-risk ARGs and suppression of interactions among high-risk ARGs, promoting its safe adoption in agroecosystems. Overall, this study provides a comprehensive antibiotic risk assessment framework, demonstrating straw retention as a beneficial strategy that enhances soil fertility with practically manageable resistance risks in agroecosystems.http://www.sciencedirect.com/science/article/pii/S0147651325009753Straw retentionSeasonally frozen agroecosystemAntibiotic resistance geneRisk assessmentMetagenomic sequencing
spellingShingle Yi Wu
Yi Fan
Yiheng Tao
Quankuan Guo
Shuang Pang
Wei Yang
Ximei Zhang
Seasonal dynamics and risk assessment of antibiotic resistome in straw-retained agroecosystems
Ecotoxicology and Environmental Safety
Straw retention
Seasonally frozen agroecosystem
Antibiotic resistance gene
Risk assessment
Metagenomic sequencing
title Seasonal dynamics and risk assessment of antibiotic resistome in straw-retained agroecosystems
title_full Seasonal dynamics and risk assessment of antibiotic resistome in straw-retained agroecosystems
title_fullStr Seasonal dynamics and risk assessment of antibiotic resistome in straw-retained agroecosystems
title_full_unstemmed Seasonal dynamics and risk assessment of antibiotic resistome in straw-retained agroecosystems
title_short Seasonal dynamics and risk assessment of antibiotic resistome in straw-retained agroecosystems
title_sort seasonal dynamics and risk assessment of antibiotic resistome in straw retained agroecosystems
topic Straw retention
Seasonally frozen agroecosystem
Antibiotic resistance gene
Risk assessment
Metagenomic sequencing
url http://www.sciencedirect.com/science/article/pii/S0147651325009753
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