High Altitude May Protect Against the Early Development of Irreversible Pulmonary Hypertension in Patients With Congenital Heart Disease

High Altitude May Protect Against the Early Development of Irreversible Pulmonary Hypertension in Patients With Congenital Heart Disease

ABSTRACT Congenital heart disease (CHD) occurs at increased prevalence at high altitude, but there may be a paradoxical later onset of the development of Eisenmenger syndrome. We hypothesized that congenital heart disease patients at high altitude are protected from an early onset of irreversible pu...

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Main Authors: Inge vonAlvensleben, Brian B. Graham, Gustavo A. Balanza, Carlos Brockmann, Ericka C. Pérez, Ximena Y. Vicente, Carla Arteaga, Claudia Scherer, Franz P. Freudenthal, Rubin M. Tuder, Alexandra Heath
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Pulmonary Circulation
Subjects:
chronic hypobaric hypoxemia
congenital heart defect
Eisenmenger syndrome
high altitude
lung biopsy in cardiac shunts
Online Access:https://doi.org/10.1002/pul2.70049
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