Development and Characterization of Photoinduced Acrylamide-Grafted Polylactide Films for Biomedical Applications
Surface grafting of biodegradable/biocompatible polylactide (PLA) films by a UV-assisted reaction has been developed by employing a hydrophilic acrylamide (Am) monomer, an N,N′-methylenebisacrylamide (MBAm) cross-linker, and a camphorquinone (CQ)/N,N′-dimethylaminoethylmethacrylate (DMAEMA) photoini...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | International Journal of Polymer Science |
| Online Access: | http://dx.doi.org/10.1155/2017/5651398 |
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| author | Mijanur Rahman Paiboon Sreearunothai Pakorn Opaprakasit |
| author_facet | Mijanur Rahman Paiboon Sreearunothai Pakorn Opaprakasit |
| author_sort | Mijanur Rahman |
| collection | DOAJ |
| description | Surface grafting of biodegradable/biocompatible polylactide (PLA) films by a UV-assisted reaction has been developed by employing a hydrophilic acrylamide (Am) monomer, an N,N′-methylenebisacrylamide (MBAm) cross-linker, and a camphorquinone (CQ)/N,N′-dimethylaminoethylmethacrylate (DMAEMA) photoinitiator/coinitiator system. The accomplishment of the process is confirmed by FTIR and XPS analyses. Physicochemical changes of the grafted PLA films are evaluated in terms of chemical structures, radiation-induced degradation followed by crystallization, morphology, thermal properties, and mechanical behavior. The results reveal that a low degree of PLA degradation through chain scission is observed in both blank and grafted PLA films. This generates more polar chain ends that can further induce crystallization. Results from contact angle measurements indicate that the grafted films have higher hydrophilicity and pH-responsive behavior. The incorporation of PAm on the film’s surface and the induced crystallization lead to improvements in certain aspects of mechanical properties of the films. The materials have high potential for use in biomedical and environmental applications, such as cell culture substrates or scaffolds or pH-sensitive absorbents. |
| format | Article |
| id | doaj-art-73b1e2a6b2174fd5af2cd56ec819fd45 |
| institution | Kabale University |
| issn | 1687-9422 1687-9430 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Polymer Science |
| spelling | doaj-art-73b1e2a6b2174fd5af2cd56ec819fd452025-08-20T03:33:53ZengWileyInternational Journal of Polymer Science1687-94221687-94302017-01-01201710.1155/2017/56513985651398Development and Characterization of Photoinduced Acrylamide-Grafted Polylactide Films for Biomedical ApplicationsMijanur Rahman0Paiboon Sreearunothai1Pakorn Opaprakasit2School of Biochemical Engineering and Technology, Sirindhorn International Institute of Technology (SIIT), Thammasat University, Pathum Thani 12121, ThailandSchool of Biochemical Engineering and Technology, Sirindhorn International Institute of Technology (SIIT), Thammasat University, Pathum Thani 12121, ThailandSchool of Biochemical Engineering and Technology, Sirindhorn International Institute of Technology (SIIT), Thammasat University, Pathum Thani 12121, ThailandSurface grafting of biodegradable/biocompatible polylactide (PLA) films by a UV-assisted reaction has been developed by employing a hydrophilic acrylamide (Am) monomer, an N,N′-methylenebisacrylamide (MBAm) cross-linker, and a camphorquinone (CQ)/N,N′-dimethylaminoethylmethacrylate (DMAEMA) photoinitiator/coinitiator system. The accomplishment of the process is confirmed by FTIR and XPS analyses. Physicochemical changes of the grafted PLA films are evaluated in terms of chemical structures, radiation-induced degradation followed by crystallization, morphology, thermal properties, and mechanical behavior. The results reveal that a low degree of PLA degradation through chain scission is observed in both blank and grafted PLA films. This generates more polar chain ends that can further induce crystallization. Results from contact angle measurements indicate that the grafted films have higher hydrophilicity and pH-responsive behavior. The incorporation of PAm on the film’s surface and the induced crystallization lead to improvements in certain aspects of mechanical properties of the films. The materials have high potential for use in biomedical and environmental applications, such as cell culture substrates or scaffolds or pH-sensitive absorbents.http://dx.doi.org/10.1155/2017/5651398 |
| spellingShingle | Mijanur Rahman Paiboon Sreearunothai Pakorn Opaprakasit Development and Characterization of Photoinduced Acrylamide-Grafted Polylactide Films for Biomedical Applications International Journal of Polymer Science |
| title | Development and Characterization of Photoinduced Acrylamide-Grafted Polylactide Films for Biomedical Applications |
| title_full | Development and Characterization of Photoinduced Acrylamide-Grafted Polylactide Films for Biomedical Applications |
| title_fullStr | Development and Characterization of Photoinduced Acrylamide-Grafted Polylactide Films for Biomedical Applications |
| title_full_unstemmed | Development and Characterization of Photoinduced Acrylamide-Grafted Polylactide Films for Biomedical Applications |
| title_short | Development and Characterization of Photoinduced Acrylamide-Grafted Polylactide Films for Biomedical Applications |
| title_sort | development and characterization of photoinduced acrylamide grafted polylactide films for biomedical applications |
| url | http://dx.doi.org/10.1155/2017/5651398 |
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