Fungal sepsis in a 7-month-old female: diagnosis through peripheral blood smear

Fungal sepsis in a 7-month-old female: diagnosis through peripheral blood smear

We report a case of a 7-month-old female with prolonged high-grade fever unresponsive to broad-spectrum antibiotics and antimalarial drugs. Despite negative cultures and imaging, a Giemsa-stained peripheral blood smear on day 28 revealed yeast cells, suggesting fungal sepsis in the context of prolon...

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Bibliographic Details
Main Authors: Yihun Bedaso, Tadesse Alemayehu, Amanuel Anegagregn Bizuneh, Dereje Zeleke Haile, Seble Seifu Zeleke, Mekdes Shifeta, Agete Tadewos Hirigo
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Medical Mycology Case Reports
Subjects:
Fever
Peripheral blood smear
Yeast cells
Fungal sepsis
Online Access:http://www.sciencedirect.com/science/article/pii/S221175392500017X
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Summary:We report a case of a 7-month-old female with prolonged high-grade fever unresponsive to broad-spectrum antibiotics and antimalarial drugs. Despite negative cultures and imaging, a Giemsa-stained peripheral blood smear on day 28 revealed yeast cells, suggesting fungal sepsis in the context of prolonged antibiotic exposure and thrombocytopenia. The patient responded well to oral fluconazole, with full clinical recovery. This case underscores the value of peripheral blood smear examination in diagnosing yeast infections in resource-limited settings.
ISSN:2211-7539

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