Antithrombotic Therapy after Bleeding in Elderly Polimorbid Patient: Our Time Challenge

In recent years, there has been a clear trend towards an increase in the number of elderly patients suffering from several polymorbid diseases, which considerably complicates the forecast and tactics of management. A clinical case of an elderly patient, suffering for a long time from type 2 diabetes...

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Main Authors: M. R. Atabegashvili, M. Yu. Gilyarov, E. V. Konstantinova, A. N. Kostina, A. P. Nesterov, T. D. Pakharkova, A. E. Udovichenko
Format: Article
Language:English
Published: Столичная издательская компания 2018-09-01
Series:Рациональная фармакотерапия в кардиологии
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Online Access:https://www.rpcardio.online/jour/article/view/1721
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author M. R. Atabegashvili
M. Yu. Gilyarov
E. V. Konstantinova
A. N. Kostina
A. P. Nesterov
T. D. Pakharkova
A. E. Udovichenko
author_facet M. R. Atabegashvili
M. Yu. Gilyarov
E. V. Konstantinova
A. N. Kostina
A. P. Nesterov
T. D. Pakharkova
A. E. Udovichenko
author_sort M. R. Atabegashvili
collection DOAJ
description In recent years, there has been a clear trend towards an increase in the number of elderly patients suffering from several polymorbid diseases, which considerably complicates the forecast and tactics of management. A clinical case of an elderly patient, suffering for a long time from type 2 diabetes mellitus, receiving insulin and treated with programmed hemodialysis due to terminal chronic renal failure, and suffering from atrial fibrillation in permanent form, is presented. The patient was hospitalized in theCityClinicalHospital№1 named after N.I. Pirogov due to acute repeated myocardial infarction. An emergency percutaneous coronary intervention was performed, the infarct-dependent artery was stented with a drug-eluted stent. The postoperative period complicated by the development of acute blood loss associated with bleeding from the upper sections of the gastrointestinal tract, and severe anemia of the combined genesis (posthemorrhagic, renal). This situation required doctors to make non-standard decisions in the choice of antithrombotic therapy. This clinical case illustrates the difficulties in elderly polymorbid patient management in real clinical practice and the controversial issues arising in the prescribing the antithrombotic therapy, especially after bleeding had developed. The supporting guidelines cannot answer all the questions which the daily practice poses to the doctor. In each case, the resumption of antithrombotic therapy and its optimal choice for an elderly polymorbid patient with developed bleeding is the subject of discussion and presented a real challenge for the treating physician.
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institution Kabale University
issn 1819-6446
2225-3653
language English
publishDate 2018-09-01
publisher Столичная издательская компания
record_format Article
series Рациональная фармакотерапия в кардиологии
spelling doaj-art-73a7a65a34e04c2c8285e629478043e02025-08-23T10:00:29ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532018-09-0114452452810.20996/1819-6446-2018-14-4-524-5281503Antithrombotic Therapy after Bleeding in Elderly Polimorbid Patient: Our Time ChallengeM. R. Atabegashvili0M. Yu. Gilyarov1E. V. Konstantinova2A. N. Kostina3A. P. Nesterov4T. D. Pakharkova5A. E. Udovichenko6City Clinical Hospital №1 named after N.I. PirogovCity Clinical Hospital №1 named after N.I. Pirogov; I.M. Sechenov First Moscow State Medical University (Sechenov University)City Clinical Hospital №1 named after N.I. Pirogov; Pirogov Russian National Research Medical UniversityI.M. Sechenov First Moscow State Medical University (Sechenov University)City Clinical Hospital №1 named after N.I. PirogovI.M. Sechenov First Moscow State Medical University (Sechenov University)City Clinical Hospital №1 named after N.I. Pirogov; I.M. Sechenov First Moscow State Medical University (Sechenov University)In recent years, there has been a clear trend towards an increase in the number of elderly patients suffering from several polymorbid diseases, which considerably complicates the forecast and tactics of management. A clinical case of an elderly patient, suffering for a long time from type 2 diabetes mellitus, receiving insulin and treated with programmed hemodialysis due to terminal chronic renal failure, and suffering from atrial fibrillation in permanent form, is presented. The patient was hospitalized in theCityClinicalHospital№1 named after N.I. Pirogov due to acute repeated myocardial infarction. An emergency percutaneous coronary intervention was performed, the infarct-dependent artery was stented with a drug-eluted stent. The postoperative period complicated by the development of acute blood loss associated with bleeding from the upper sections of the gastrointestinal tract, and severe anemia of the combined genesis (posthemorrhagic, renal). This situation required doctors to make non-standard decisions in the choice of antithrombotic therapy. This clinical case illustrates the difficulties in elderly polymorbid patient management in real clinical practice and the controversial issues arising in the prescribing the antithrombotic therapy, especially after bleeding had developed. The supporting guidelines cannot answer all the questions which the daily practice poses to the doctor. In each case, the resumption of antithrombotic therapy and its optimal choice for an elderly polymorbid patient with developed bleeding is the subject of discussion and presented a real challenge for the treating physician.https://www.rpcardio.online/jour/article/view/1721elderly patientacute coronary syndromepercutaneous coronary interventionrenal dysfunctionhemodialysisatrial fibrillationantithrombotic therapybleedingsafety of treatment
spellingShingle M. R. Atabegashvili
M. Yu. Gilyarov
E. V. Konstantinova
A. N. Kostina
A. P. Nesterov
T. D. Pakharkova
A. E. Udovichenko
Antithrombotic Therapy after Bleeding in Elderly Polimorbid Patient: Our Time Challenge
Рациональная фармакотерапия в кардиологии
elderly patient
acute coronary syndrome
percutaneous coronary intervention
renal dysfunction
hemodialysis
atrial fibrillation
antithrombotic therapy
bleeding
safety of treatment
title Antithrombotic Therapy after Bleeding in Elderly Polimorbid Patient: Our Time Challenge
title_full Antithrombotic Therapy after Bleeding in Elderly Polimorbid Patient: Our Time Challenge
title_fullStr Antithrombotic Therapy after Bleeding in Elderly Polimorbid Patient: Our Time Challenge
title_full_unstemmed Antithrombotic Therapy after Bleeding in Elderly Polimorbid Patient: Our Time Challenge
title_short Antithrombotic Therapy after Bleeding in Elderly Polimorbid Patient: Our Time Challenge
title_sort antithrombotic therapy after bleeding in elderly polimorbid patient our time challenge
topic elderly patient
acute coronary syndrome
percutaneous coronary intervention
renal dysfunction
hemodialysis
atrial fibrillation
antithrombotic therapy
bleeding
safety of treatment
url https://www.rpcardio.online/jour/article/view/1721
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AT myugilyarov antithrombotictherapyafterbleedinginelderlypolimorbidpatientourtimechallenge
AT evkonstantinova antithrombotictherapyafterbleedinginelderlypolimorbidpatientourtimechallenge
AT ankostina antithrombotictherapyafterbleedinginelderlypolimorbidpatientourtimechallenge
AT apnesterov antithrombotictherapyafterbleedinginelderlypolimorbidpatientourtimechallenge
AT tdpakharkova antithrombotictherapyafterbleedinginelderlypolimorbidpatientourtimechallenge
AT aeudovichenko antithrombotictherapyafterbleedinginelderlypolimorbidpatientourtimechallenge