TRAF2 regulates the progression of pulmonary fibrosis through β-catenin-Snail signaling pathway

TRAF2 regulates the progression of pulmonary fibrosis through β-catenin-Snail signaling pathway

IntroductionPulmonary fibrosis (PF) is a devastating lung disease characterized by excessive extracellular matrix deposition and impaired pulmonary function, with limited therapeutic options. The pathogenesis of PF involves a complex network of molecular events, including epithelial-mesenchymal tran...

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Main Authors: Zhijie Wan, Jingwen Gu, Wanli Duan, Yuanyuan Chen, Shuya Song, Jingyu Luo, Xide Zhang, Yanyong Yang, Fu Gao, Ying Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Public Health
Subjects:
TRAF2
pulmonary fibrosis
EMT
β-catenin
Snail
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1582860/full
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