A Review on In Vitro Evaluation of Chemical and Physical Digestion for Controlling Gastric Digestion of Food
Food digestion in the gastrointestinal is a series of processes consisting of chemical and physical digestion. Recently, developing foods with controlled digestion in the stomach may attract more attention. Hydrogel foods are useful tools for designing foods with controlled digestion because it is r...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-04-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/14/8/1435 |
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| author | Hiroyuki Kozu Isao Kobayashi Sosaku Ichikawa |
| author_facet | Hiroyuki Kozu Isao Kobayashi Sosaku Ichikawa |
| author_sort | Hiroyuki Kozu |
| collection | DOAJ |
| description | Food digestion in the gastrointestinal is a series of processes consisting of chemical and physical digestion. Recently, developing foods with controlled digestion in the stomach may attract more attention. Hydrogel foods are useful tools for designing foods with controlled digestion because it is relatively easy to design their food characteristics by adjusting the type and content of the additives. This review introduces the latest status of in vitro gastric digestion as a food characterization system. The in vitro evaluation of chemical gastric digestion by gastric acid and digestive enzymes focuses on INFOGEST-standardized gastrointestinal digestion protocols for healthy adults, infants, and older adults. For the in vitro evaluation of physical gastric digestion by peristalsis, the current development of gastrointestinal tract devices that precisely or efficiently simulate the shape of the stomach and gastric peristalsis is described. In addition, we introduce studies that have utilized these devices to investigate the gastric digestion behavior of hydrocolloid foods with different mechanical characteristics. |
| format | Article |
| id | doaj-art-7384301773c74bbea677ecb8dd5da5b8 |
| institution | OA Journals |
| issn | 2304-8158 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj-art-7384301773c74bbea677ecb8dd5da5b82025-08-20T02:18:16ZengMDPI AGFoods2304-81582025-04-01148143510.3390/foods14081435A Review on In Vitro Evaluation of Chemical and Physical Digestion for Controlling Gastric Digestion of FoodHiroyuki Kozu0Isao Kobayashi1Sosaku Ichikawa2Institute of Food Research, NARO, 2-1-12 Kannondai, Tsukuba 305–8642, Ibaraki, JapanInstitute of Food Research, NARO, 2-1-12 Kannondai, Tsukuba 305–8642, Ibaraki, JapanInstitute of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305–8572, Ibaraki, JapanFood digestion in the gastrointestinal is a series of processes consisting of chemical and physical digestion. Recently, developing foods with controlled digestion in the stomach may attract more attention. Hydrogel foods are useful tools for designing foods with controlled digestion because it is relatively easy to design their food characteristics by adjusting the type and content of the additives. This review introduces the latest status of in vitro gastric digestion as a food characterization system. The in vitro evaluation of chemical gastric digestion by gastric acid and digestive enzymes focuses on INFOGEST-standardized gastrointestinal digestion protocols for healthy adults, infants, and older adults. For the in vitro evaluation of physical gastric digestion by peristalsis, the current development of gastrointestinal tract devices that precisely or efficiently simulate the shape of the stomach and gastric peristalsis is described. In addition, we introduce studies that have utilized these devices to investigate the gastric digestion behavior of hydrocolloid foods with different mechanical characteristics.https://www.mdpi.com/2304-8158/14/8/1435food digestion controlgastric digestiongastric peristalsisin vitro digestion evaluationchemical digestionphysical digestion |
| spellingShingle | Hiroyuki Kozu Isao Kobayashi Sosaku Ichikawa A Review on In Vitro Evaluation of Chemical and Physical Digestion for Controlling Gastric Digestion of Food Foods food digestion control gastric digestion gastric peristalsis in vitro digestion evaluation chemical digestion physical digestion |
| title | A Review on In Vitro Evaluation of Chemical and Physical Digestion for Controlling Gastric Digestion of Food |
| title_full | A Review on In Vitro Evaluation of Chemical and Physical Digestion for Controlling Gastric Digestion of Food |
| title_fullStr | A Review on In Vitro Evaluation of Chemical and Physical Digestion for Controlling Gastric Digestion of Food |
| title_full_unstemmed | A Review on In Vitro Evaluation of Chemical and Physical Digestion for Controlling Gastric Digestion of Food |
| title_short | A Review on In Vitro Evaluation of Chemical and Physical Digestion for Controlling Gastric Digestion of Food |
| title_sort | review on in vitro evaluation of chemical and physical digestion for controlling gastric digestion of food |
| topic | food digestion control gastric digestion gastric peristalsis in vitro digestion evaluation chemical digestion physical digestion |
| url | https://www.mdpi.com/2304-8158/14/8/1435 |
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