Magnetic properties of polymeric acrylic acid hydrogel dosimeter for radiotherapy applications
Abstract The present study introduces the first magnetic characterization of a hydrogel dosimeter comprising acrylic acid synthesized within a polyvinyl alcohol matrix. The study aims to accurately assess ionizing radiation dose distributions, making it a valuable tool for radiotherapy treatment. Th...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-96276-0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849699862348562432 |
|---|---|
| author | Belal Moftah Khalid A. Rabaeh Akram A. Moussa Md Abdullah Al Kafi Abdullah S. Bani Issa |
| author_facet | Belal Moftah Khalid A. Rabaeh Akram A. Moussa Md Abdullah Al Kafi Abdullah S. Bani Issa |
| author_sort | Belal Moftah |
| collection | DOAJ |
| description | Abstract The present study introduces the first magnetic characterization of a hydrogel dosimeter comprising acrylic acid synthesized within a polyvinyl alcohol matrix. The study aims to accurately assess ionizing radiation dose distributions, making it a valuable tool for radiotherapy treatment. The hydrogel was irradiated to a 1–60 Gy dose range using a medical linear accelerator with dose rates of 100–600 MU/min and radiation beam energies of 6, 10, and 15 MV. The developed dosimeter was synthesized by irradiation-triggered polymerization, and the polymerization degree was indirectly quantified by monitoring the positive alterations in the nuclear magnetic resonance spin‒spin relaxation rate. The polymeric hydrogel dosimeter demonstrated an exceptional dose response with an NMR sensitivity of 0.26 Gy⁻¹s⁻¹, which is 20 times more than the sensitivity of the same gel when measured optically in our previous study. Moreover, it exhibited consistent performance regardless of the beam energy or dose rate. |
| format | Article |
| id | doaj-art-73809e79d76b48148db03460e7341505 |
| institution | DOAJ |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-73809e79d76b48148db03460e73415052025-08-20T03:18:27ZengNature PortfolioScientific Reports2045-23222025-04-011511810.1038/s41598-025-96276-0Magnetic properties of polymeric acrylic acid hydrogel dosimeter for radiotherapy applicationsBelal Moftah0Khalid A. Rabaeh1Akram A. Moussa2Md Abdullah Al Kafi3Abdullah S. Bani Issa4Biomedical Physics Department, King Faisal Specialist Hospital and Research CentreMedical Imaging Department, Faculty of Applied Medical Sciences, The Hashemite UniversityBiomedical Physics Department, King Faisal Specialist Hospital and Research CentreBiomedical Physics Department, King Faisal Specialist Hospital and Research CentrePhysics Department, Faculty of Science, Yarmouk UniversityAbstract The present study introduces the first magnetic characterization of a hydrogel dosimeter comprising acrylic acid synthesized within a polyvinyl alcohol matrix. The study aims to accurately assess ionizing radiation dose distributions, making it a valuable tool for radiotherapy treatment. The hydrogel was irradiated to a 1–60 Gy dose range using a medical linear accelerator with dose rates of 100–600 MU/min and radiation beam energies of 6, 10, and 15 MV. The developed dosimeter was synthesized by irradiation-triggered polymerization, and the polymerization degree was indirectly quantified by monitoring the positive alterations in the nuclear magnetic resonance spin‒spin relaxation rate. The polymeric hydrogel dosimeter demonstrated an exceptional dose response with an NMR sensitivity of 0.26 Gy⁻¹s⁻¹, which is 20 times more than the sensitivity of the same gel when measured optically in our previous study. Moreover, it exhibited consistent performance regardless of the beam energy or dose rate.https://doi.org/10.1038/s41598-025-96276-0RadiotherapyRadiation dosimetryQuality assurancePolymer hydrogelSpectrophotometryNuclear magnetic resonance |
| spellingShingle | Belal Moftah Khalid A. Rabaeh Akram A. Moussa Md Abdullah Al Kafi Abdullah S. Bani Issa Magnetic properties of polymeric acrylic acid hydrogel dosimeter for radiotherapy applications Scientific Reports Radiotherapy Radiation dosimetry Quality assurance Polymer hydrogel Spectrophotometry Nuclear magnetic resonance |
| title | Magnetic properties of polymeric acrylic acid hydrogel dosimeter for radiotherapy applications |
| title_full | Magnetic properties of polymeric acrylic acid hydrogel dosimeter for radiotherapy applications |
| title_fullStr | Magnetic properties of polymeric acrylic acid hydrogel dosimeter for radiotherapy applications |
| title_full_unstemmed | Magnetic properties of polymeric acrylic acid hydrogel dosimeter for radiotherapy applications |
| title_short | Magnetic properties of polymeric acrylic acid hydrogel dosimeter for radiotherapy applications |
| title_sort | magnetic properties of polymeric acrylic acid hydrogel dosimeter for radiotherapy applications |
| topic | Radiotherapy Radiation dosimetry Quality assurance Polymer hydrogel Spectrophotometry Nuclear magnetic resonance |
| url | https://doi.org/10.1038/s41598-025-96276-0 |
| work_keys_str_mv | AT belalmoftah magneticpropertiesofpolymericacrylicacidhydrogeldosimeterforradiotherapyapplications AT khalidarabaeh magneticpropertiesofpolymericacrylicacidhydrogeldosimeterforradiotherapyapplications AT akramamoussa magneticpropertiesofpolymericacrylicacidhydrogeldosimeterforradiotherapyapplications AT mdabdullahalkafi magneticpropertiesofpolymericacrylicacidhydrogeldosimeterforradiotherapyapplications AT abdullahsbaniissa magneticpropertiesofpolymericacrylicacidhydrogeldosimeterforradiotherapyapplications |