Epithelioid Trophoblastic Tumor—A Challenge to Manage due to Its Rare Existence: A Case Report with Review of Literature

Epithelioid trophoblastic tumor (ETT) is the rarest type of gestational trophoblastic neoplasia. It has variable presentations and is an aggressive tumor. Because of its rarity, it is difficult to establish an appropriate diagnosis, management, and follow-up. A woman of age 45 years postmenopausal s...

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Main Authors: Neetha Nandan, Vijith Shetty, Roopali Chaturvedi
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2024-12-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788777
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author Neetha Nandan
Vijith Shetty
Roopali Chaturvedi
author_facet Neetha Nandan
Vijith Shetty
Roopali Chaturvedi
author_sort Neetha Nandan
collection DOAJ
description Epithelioid trophoblastic tumor (ETT) is the rarest type of gestational trophoblastic neoplasia. It has variable presentations and is an aggressive tumor. Because of its rarity, it is difficult to establish an appropriate diagnosis, management, and follow-up. A woman of age 45 years postmenopausal status with an antecedent term pregnancy 13 years back was diagnosed to have ETT in the hysterectomy specimen. She had come with urinary retention as the tumor was infiltrating the bladder. Beta-human chorionic gonadotropin levels were normal. Immunohistochemistry confirmed the diagnosis. Though metastatic workup was normal, adjuvant multiagent chemotherapy was given as the bladder flap margin was not free of tumor cells and antecedent pregnancy was > 4 years. Every new case of ETT needs to be reported to bring about more awareness of the unusual presentations, and it may help come to a consensus for appropriate management.
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publishDate 2024-12-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
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series Indian Journal of Medical and Paediatric Oncology
spelling doaj-art-737b4c22048a42a2986d3aba241a45a32025-08-20T02:32:41ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292024-12-01450655055310.1055/s-0044-1788777Epithelioid Trophoblastic Tumor—A Challenge to Manage due to Its Rare Existence: A Case Report with Review of LiteratureNeetha Nandan0https://orcid.org/0000-0003-3831-9642Vijith Shetty1Roopali Chaturvedi2Department of Obstetrics and Gynaecology, K.S. Hegde Medical Academy, NITTE (Deemed to be University), Mangaluru, Karnataka, IndiaDepartment of Medical Oncology, K.S. Hegde Medical Academy, NITTE (Deemed to be University), Mangaluru, Karnataka IndiaDepartment of Obstetrics and Gynaecology, K.S. Hegde Medical Academy, NITTE (Deemed to be University), Mangaluru, Karnataka, IndiaEpithelioid trophoblastic tumor (ETT) is the rarest type of gestational trophoblastic neoplasia. It has variable presentations and is an aggressive tumor. Because of its rarity, it is difficult to establish an appropriate diagnosis, management, and follow-up. A woman of age 45 years postmenopausal status with an antecedent term pregnancy 13 years back was diagnosed to have ETT in the hysterectomy specimen. She had come with urinary retention as the tumor was infiltrating the bladder. Beta-human chorionic gonadotropin levels were normal. Immunohistochemistry confirmed the diagnosis. Though metastatic workup was normal, adjuvant multiagent chemotherapy was given as the bladder flap margin was not free of tumor cells and antecedent pregnancy was > 4 years. Every new case of ETT needs to be reported to bring about more awareness of the unusual presentations, and it may help come to a consensus for appropriate management.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788777epithelioid trophoblastic tumorgestational trophoblastic neoplasiaplacental site trophoblastic tumor
spellingShingle Neetha Nandan
Vijith Shetty
Roopali Chaturvedi
Epithelioid Trophoblastic Tumor—A Challenge to Manage due to Its Rare Existence: A Case Report with Review of Literature
Indian Journal of Medical and Paediatric Oncology
epithelioid trophoblastic tumor
gestational trophoblastic neoplasia
placental site trophoblastic tumor
title Epithelioid Trophoblastic Tumor—A Challenge to Manage due to Its Rare Existence: A Case Report with Review of Literature
title_full Epithelioid Trophoblastic Tumor—A Challenge to Manage due to Its Rare Existence: A Case Report with Review of Literature
title_fullStr Epithelioid Trophoblastic Tumor—A Challenge to Manage due to Its Rare Existence: A Case Report with Review of Literature
title_full_unstemmed Epithelioid Trophoblastic Tumor—A Challenge to Manage due to Its Rare Existence: A Case Report with Review of Literature
title_short Epithelioid Trophoblastic Tumor—A Challenge to Manage due to Its Rare Existence: A Case Report with Review of Literature
title_sort epithelioid trophoblastic tumor a challenge to manage due to its rare existence a case report with review of literature
topic epithelioid trophoblastic tumor
gestational trophoblastic neoplasia
placental site trophoblastic tumor
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1788777
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AT vijithshetty epithelioidtrophoblastictumorachallengetomanageduetoitsrareexistenceacasereportwithreviewofliterature
AT roopalichaturvedi epithelioidtrophoblastictumorachallengetomanageduetoitsrareexistenceacasereportwithreviewofliterature