Selective whole-genome amplification reveals population genetics of Leishmania braziliensis directly from patient skin biopsies.

Selective whole-genome amplification reveals population genetics of Leishmania braziliensis directly from patient skin biopsies.

In Brazil, Leishmania braziliensis is the main causative agent of the neglected tropical disease, cutaneous leishmaniasis (CL). CL presents on a spectrum of disease severity with a high rate of treatment failure. Yet the parasite factors that contribute to disease presentation and treatment outcome...

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Main Authors: Olivia A Pilling, João L Reis-Cunha, Cooper A Grace, Alexander S F Berry, Matthew W Mitchell, Jane A Yu, Clara R Malekshahi, Elise Krespan, Christina K Go, Cláudia Lombana, Yun S Song, Camila F Amorim, Alexsandro S Lago, Lucas P Carvalho, Edgar M Carvalho, Dustin Brisson, Phillip Scott, Daniel C Jeffares, Daniel P Beiting
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011230
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