Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury

Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury

Abstract Ferroptosis is a newly identified cell death triggered by iron‐induced lipid peroxidation. Numerous studies reveal that ferroptosis participates in multiple types of tissue injury including ischaemia–reperfusion (I/R) injury and doxorubicin (Dox)‐induced damage. Targeting ferroptosis is a p...

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Main Authors: Xiao Zhuang, Shuang Shi, Shuo Liu, Yaqiong Jiao, Bin Huang, Yinghong Yang, Li Yang, Xinquan Yang, Hui Wang, Chunhui Liang, Dandan Song, Huaxiang Yu, Dan Zou, Qi Sun, Shu Yang, Chengqian Yin, Jian Li, Yiming Liu, Junxia Min, Fudi Wang, Yong Nian, Lutao Du, Bo Chu
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
dipyridamole
ferroptosis
SLC7A11
tissue injury
Online Access:https://doi.org/10.1002/advs.202500566
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