On the feasibility of producing Lu-177 in the IEA-R1 reactor via the direct route
Over the last years the 177Lu radioisotope has attracted great interest for the use in therapeutic and diagnostic procedures simultaneously, being what is now called a theranostic radioisotope. There are mainly two ways of producing this radioisotope, by direct neutron capture in a 176Lu target (the...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)
2021-04-01
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| Series: | Brazilian Journal of Radiation Sciences |
| Subjects: | |
| Online Access: | https://bjrs.org.br/revista/index.php/REVISTA/article/view/1411 |
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| Summary: | Over the last years the 177Lu radioisotope has attracted great interest for the use in therapeutic and diagnostic procedures simultaneously, being what is now called a theranostic radioisotope. There are mainly two ways of producing this radioisotope, by direct neutron capture in a 176Lu target (the “direct route") or by irradiating a 176Yb sample, producing 177Yb that will then decay to 177Lu (also referred as the “indirect route”). In this work the feasibility of producing 177Lu in the IEA-R1 nuclear reactor via the direct route was assessed, and the specific activity that could be obtained was estimated both experimentally and theoretically, allowing for a discussion on the feasibility of commercially producing 177Lu by 176Lu neutron capture in the IEA-R1 reactor. |
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| ISSN: | 2319-0612 |