Malignant transformation of pleomorphic xanthoastrocytoma: case report

We report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new oper...

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Main Authors: Oswaldo Ignácio de Tella Jr, Marco Antonio Herculano, Mirto Nelso Prandini, João Norberto Stavale, Paulo Henrique Aguiar
Format: Article
Language:English
Published: Thieme Revinter Publicações 2003-03-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000100020&tlng=en
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author Oswaldo Ignácio de Tella Jr
Marco Antonio Herculano
Mirto Nelso Prandini
João Norberto Stavale
Paulo Henrique Aguiar
author_facet Oswaldo Ignácio de Tella Jr
Marco Antonio Herculano
Mirto Nelso Prandini
João Norberto Stavale
Paulo Henrique Aguiar
author_sort Oswaldo Ignácio de Tella Jr
collection DOAJ
description We report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new operation, which revealed a friable tumor, easily differentiated from the normal parenchyma, with cystic components. The histopathological examination demonstrated pleomorphic xanthoastrocytoma with malignant transformation. Histologically, the tumor at first procedure was composed of pleomorphic astrocytes with multinucleated and foamy cells. A rare case of malignant transformation in pleomorphic xanthoastrocytoma is presented, discussed and illustrated in this paper.
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series Arquivos de Neuro-Psiquiatria
spelling doaj-art-735287024c6d408cb3b3c060fa52d2db2025-08-20T03:19:08ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272003-03-01611104106Malignant transformation of pleomorphic xanthoastrocytoma: case reportOswaldo Ignácio de Tella Jr0Marco Antonio Herculano1Mirto Nelso Prandini2João Norberto Stavale3Paulo Henrique Aguiar4Federal University of São PauloJundiai Medicine SchoolFederal University of São PauloFederal University of São PauloState University of São PauloWe report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new operation, which revealed a friable tumor, easily differentiated from the normal parenchyma, with cystic components. The histopathological examination demonstrated pleomorphic xanthoastrocytoma with malignant transformation. Histologically, the tumor at first procedure was composed of pleomorphic astrocytes with multinucleated and foamy cells. A rare case of malignant transformation in pleomorphic xanthoastrocytoma is presented, discussed and illustrated in this paper.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000100020&tlng=enxanthoastrocytomaastrocytomatumorhistopathology
spellingShingle Oswaldo Ignácio de Tella Jr
Marco Antonio Herculano
Mirto Nelso Prandini
João Norberto Stavale
Paulo Henrique Aguiar
Malignant transformation of pleomorphic xanthoastrocytoma: case report
Arquivos de Neuro-Psiquiatria
xanthoastrocytoma
astrocytoma
tumor
histopathology
title Malignant transformation of pleomorphic xanthoastrocytoma: case report
title_full Malignant transformation of pleomorphic xanthoastrocytoma: case report
title_fullStr Malignant transformation of pleomorphic xanthoastrocytoma: case report
title_full_unstemmed Malignant transformation of pleomorphic xanthoastrocytoma: case report
title_short Malignant transformation of pleomorphic xanthoastrocytoma: case report
title_sort malignant transformation of pleomorphic xanthoastrocytoma case report
topic xanthoastrocytoma
astrocytoma
tumor
histopathology
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000100020&tlng=en
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AT mirtonelsoprandini malignanttransformationofpleomorphicxanthoastrocytomacasereport
AT joaonorbertostavale malignanttransformationofpleomorphicxanthoastrocytomacasereport
AT paulohenriqueaguiar malignanttransformationofpleomorphicxanthoastrocytomacasereport