A non-classical PUF family protein in oomycetes functions as a pre-rRNA processing regulator and a target for RNAi-based disease control.

A non-classical PUF family protein in oomycetes functions as a pre-rRNA processing regulator and a target for RNAi-based disease control.

Ribosome biogenesis is an essential and tightly regulated process linked to cell proliferation and growth. However, its regulatory mechanisms in oomycetes, a group of organisms with significant agricultural and ecological importance, remain unclear. In this study, we identify Puf4, a non-classical P...

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Main Authors: Hui Feng, Tianli Liu, Chuanxu Wan, Zhichao Zhang, Yuanchao Wang, Xiaobo Zheng, Jie Wang, Wenwu Ye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1013379
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